Supplementary Data for the Global Landscape of Human Proteins Targeted by Pathogens
Enrichments for Whole Human Network
Adenovirus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0005488
|
binding
|
1
|
0.013297183167762459
|
| 2 | GO:0031974
GO:0043233 |
membrane-enclosed lumen
organelle lumen |
1
2 |
3.4136697426708325E-4
0.005325217564182574 |
| 3 | GO:0008152
|
metabolic process
|
1
|
0.0024528764107094045
|
| 4 | GO:0008632
|
apoptotic program
|
5
|
0.0023308927885515598
|
| 5 | GO:0003676
|
nucleic acid binding
|
2
|
0.021350022995889437
|
| 6 | GO:0005667
|
transcription factor complex
|
3
|
0.0375657420407839
|
| 7 | GO:0030528
|
transcription regulator activity
|
1
|
1.0611554189987547E-8
|
| 8 | GO:0046930
|
pore complex
|
5
|
0.03135444287574812
|
| 9 | GO:0043067
|
regulation of programmed cell death
|
3
|
0.03208672051122662
|
| 10 | GO:0022402
|
cell cycle process
|
2
|
8.649667573593647E-4
|
| 11 | GO:0005634
|
nucleus
|
4
|
3.7125851092504144E-4
|
| 12 | GO:0016265
GO:0048869 GO:0048468 GO:0008219 |
death
cellular developmental process cell development cell death |
2
2 2 3 |
3.0776349346742017E-5
0.002845103886139939 6.275327629967867E-5 7.16347946138829E-5 |
| 13 | GO:0007006
GO:0046902 |
mitochondrial membrane organization and
biogenesis
regulation of mitochondrial membrane permeability |
4
5 |
0.006552444966220378
0.021153135484640807 |
| 14 | GO:0043227
GO:0043231 |
membrane-bound organelle
intracellular membrane-bound organelle |
2
3 |
0.03141693117156784
0.03164677818505241 |
| 15 | GO:0044424
GO:0005622 |
intracellular part
intracellular |
2
2 |
1.642461517061432E-4
0.0024837517963988993 |
| 16 | GO:0016208
GO:0030551 GO:0005952 |
AMP binding
cyclic nucleotide binding cAMP-dependent protein kinase complex |
5
3 3 |
0.010516624534717545
0.010654267425696202 0.002716226586690343 |
| 17 | GO:0018205
|
peptidyl-lysine modification
|
7
|
0.017706393814398005
|
| 18 | GO:0043226
|
organelle
|
1
|
6.835233158254389E-5
|
| 19 | GO:0042391
|
regulation of membrane potential
|
3
|
0.03414292345850789
|
| 20 | GO:0051607
|
defense response to virus
|
3
|
0.046109301240177
|
| 21 | GO:0032774
|
RNA biosynthetic process
|
5
|
0.013595572476488854
|
| 22 | GO:0008022
|
protein C-terminus binding
|
3
|
0.0024863500551638032
|
| 23 | GO:0043543
|
protein amino acid acylation
|
6
|
4.8155623453007115E-4
|
| 24 | GO:0006139
|
nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
|
3
|
3.061826441557558E-4
|
| 25 | GO:0005626
|
insoluble fraction
|
3
|
0.035205901512232234
|
| 26 | GO:0008134
|
transcription factor binding
|
3
|
1.4436407767127635E-5
|
| 27 | GO:0046907
|
intracellular transport
|
3
|
0.011350299814357841
|
| 28 | GO:0044237
|
cellular metabolic process
|
2
|
0.01142405502094854
|
| 29 | GO:0051427
|
hormone receptor binding
|
4
|
0.006737727437337933
|
| 30 | GO:0016746
|
transferase activity, transferring acyl groups
|
3
|
0.04579990681889163
|
| 31 | GO:0050794
GO:0065007 |
regulation of cellular process
biological regulation |
2
1 |
6.498184590152401E-9
6.342084124207449E-8 |
| 32 | GO:0003677
|
DNA binding
|
3
|
0.009170161446226885
|
| 33 | GO:0000123
|
histone acetyltransferase complex
|
4
|
0.010106928440055523
|
| 34 | GO:0032502
|
developmental process
|
1
|
0.00672194155579266
|
| 35 | GO:0001666
|
response to hypoxia
|
3
|
3.7985561253224903E-6
|
| 36 | GO:0046983
|
protein dimerization activity
|
3
|
0.0030372883356476225
|
| 37 | GO:0016570
|
histone modification
|
7
|
0.02474203070315191
|
| 38 | GO:0043283
|
biopolymer metabolic process
|
3
|
0.009838282498948572
|
| 39 | GO:0005515
|
protein binding
|
2
|
0.0072356177145532115
|
| 40 | GO:0019219
GO:0031323 GO:0019222 |
regulation of nucleobase, nucleoside, nucleotide
and nucleic acid metabolic process
regulation of cellular metabolic process regulation of metabolic process |
4
3 2 |
0.00255850004667942
7.124488420174424E-5 6.405638731858199E-5 |
| 41 | GO:0006350
|
transcription
|
4
|
0.010638936554693883
|
| 42 | GO:0007049
|
cell cycle
|
2
|
0.0011817377739370089
|
| 43 | GO:0050890
|
cognition
|
3
|
0.0344398216458412
|
Bacteria
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0031326
GO:0006417 |
regulation of cellular biosynthetic process
regulation of translation |
4
4 |
1.9397427751616063E-4
0.034953166116685745 |
| 2 | GO:0045569
|
TRAIL binding
|
3
|
0.012564387542687794
|
| 3 | GO:0030235
|
nitric-oxide synthase regulator activity
|
2
|
0.04504628747721752
|
| 4 | GO:0060089
|
molecular transducer activity
|
1
|
0.009495582719527915
|
| 5 | GO:0017171
|
serine hydrolase activity
|
3
|
0.031696406899451364
|
| 6 | GO:0051234
|
establishment of localization
|
1
|
0.04800046606860302
|
| 7 | GO:0019538
|
protein metabolic process
|
3
|
6.533494269264748E-5
|
| 8 | GO:0050896
|
response to stimulus
|
1
|
8.955776178762962E-8
|
| 9 | GO:0042611
|
MHC protein complex
|
3
|
0.04379141863588711
|
| 10 | GO:0046209
|
nitric oxide metabolic process
|
3
|
0.029040866446889677
|
| 11 | GO:0009605
|
response to external stimulus
|
2
|
0.009781628618120961
|
| 12 | GO:0008147
|
structural constituent of bone
|
2
|
0.03171843811733169
|
| 13 | GO:0044260
|
cellular macromolecule metabolic process
|
3
|
7.206936335635996E-4
|
| 14 | GO:0009893
|
positive regulation of metabolic process
|
3
|
0.0065263851652548575
|
| 15 | GO:0048468
|
cell development
|
2
|
0.013024507883873248
|
| 16 | GO:0008426
|
protein kinase C inhibitor activity
|
5
|
0.01001073017366833
|
| 17 | GO:0006955
|
immune response
|
2
|
0.031802095885765456
|
| 18 | GO:0016020
|
membrane
|
2
|
0.010539710691086326
|
| 19 | GO:0016043
|
cellular component organization and biogenesis
|
2
|
0.01649230916059446
|
| 20 | GO:0048518
|
positive regulation of biological process
|
3
|
0.0017884146821396734
|
| 21 | GO:0006952
|
defense response
|
2
|
0.014662183099391182
|
| 22 | GO:0048869
|
cellular developmental process
|
2
|
0.013052606268046692
|
| 23 | GO:0016504
|
protease activator activity
|
3
|
0.0280220799733229
|
| 24 | GO:0009889
GO:0044249 |
regulation of biosynthetic process
cellular biosynthetic process |
3
3 |
2.0909326325263176E-7
0.003117130359766685 |
| 25 | GO:0042107
GO:0042089 GO:0001816 GO:0031328 |
cytokine metabolic process
cytokine biosynthetic process cytokine production positive regulation of cellular biosynthetic process |
5
3 2 5 |
6.782553764704488E-4
6.649058449388417E-4 0.004829013595649309 0.03096845662521199 |
| 26 | GO:0007243
|
protein kinase cascade
|
5
|
0.0316205329087436
|
| 27 | GO:0002376
|
immune system process
|
1
|
2.117140995715192E-7
|
| 28 | GO:0009611
|
response to wounding
|
3
|
0.013072854361256115
|
| 29 | GO:0051246
|
regulation of protein metabolic process
|
3
|
5.38578784225347E-6
|
| 30 | GO:0009891
|
positive regulation of biosynthetic process
|
4
|
0.0013771582726089654
|
| 31 | GO:0065009
|
regulation of a molecular function
|
2
|
0.035979946938246875
|
| 32 | GO:0019904
|
protein domain specific binding
|
3
|
0.005193133873849193
|
| 33 | GO:0007250
|
activation of NF-kappaB-inducing kinase
|
7
|
0.044287506079614326
|
| 34 | GO:0001871
|
pattern binding
|
2
|
0.021484374808493304
|
| 35 | GO:0005515
|
protein binding
|
2
|
1.895491562993389E-4
|
| 36 | GO:0005488
|
binding
|
1
|
0.021828890027795138
|
| 37 | GO:0005737
|
cytoplasm
|
3
|
7.472357176715367E-4
|
| 38 | GO:0007154
|
cell communication
|
2
|
0.016583075288268856
|
| 39 | GO:0051247
|
positive regulation of protein metabolic process
|
4
|
0.023703261125551926
|
| 40 | GO:0051704
|
multi-organism process
|
1
|
0.008017849853548682
|
| 41 | GO:0051179
|
localization
|
1
|
0.01657580980128367
|
| 42 | GO:0035197
|
siRNA binding
|
4
|
0.006797848640477106
|
Chlamydia
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0048534
|
hemopoietic or lymphoid organ development
|
3
|
0.04692790402452003
|
| 2 | GO:0050896
|
response to stimulus
|
1
|
3.167721663428701E-5
|
| 3 | GO:0043028
GO:0016504 GO:0045569 |
caspase regulator activity
protease activator activity TRAIL binding |
2
3 3 |
0.012509504500918795
0.03379961218343226 2.447434223310508E-4 |
| 4 | GO:0007243
GO:0007249 |
protein kinase cascade
I-kappaB kinase/NF-kappaB cascade |
5
6 |
2.483937176086511E-4
0.0012613725365302553 |
| 5 | GO:0005515
|
protein binding
|
2
|
0.009034310425448394
|
| 6 | GO:0002376
GO:0006955 |
immune system process
immune response |
1
2 |
9.793288334439328E-8
2.50421001900024E-4 |
| 7 | GO:0019538
|
protein metabolic process
|
3
|
0.033012595843945204
|
| 8 | GO:0050794
GO:0048522 GO:0048518 |
regulation of cellular process
positive regulation of cellular process positive regulation of biological process |
2
3 3 |
0.03578084374182913
7.019424851142963E-6 1.0021044473194714E-5 |
| 9 | GO:0016265
GO:0048468 |
death
cell development |
2
2 |
0.033286259332609945
0.021183210580641675 |
| 10 | GO:0008329
|
pattern recognition receptor activity
|
4
|
0.03450265217312117
|
| 11 | GO:0045087
|
innate immune response
|
3
|
0.04013039175871185
|
| 12 | GO:0016020
|
membrane
|
2
|
1.8965726045944625E-4
|
| 13 | GO:0007250
GO:0065009 |
activation of NF-kappaB-inducing kinase
regulation of a molecular function |
7
2 |
0.004061154303393735
0.046319776899460124 |
| 14 | GO:0001871
|
pattern binding
|
2
|
0.008951261381801485
|
| 15 | GO:0051606
|
detection of stimulus
|
2
|
0.047560728455538395
|
| 16 | GO:0044425
|
membrane part
|
2
|
0.009033746626333236
|
| 17 | GO:0045357
|
regulation of interferon-beta biosynthetic
process
|
5
|
0.035668017234907
|
| 18 | GO:0005121
|
Toll binding
|
4
|
0.030955064232731123
|
| 19 | GO:0009893
GO:0031323 GO:0031325 GO:0019222 |
positive regulation of metabolic process
regulation of cellular metabolic process positive regulation of cellular metabolic process regulation of metabolic process |
3
3 4 2 |
1.6002229535914253E-4
0.0339987124941974 1.6606363365798073E-4 0.030145301203309046 |
| 20 | GO:0043235
|
receptor complex
|
3
|
0.025610106730662798
|
| 21 | GO:0001530
|
lipopolysaccharide binding
|
3
|
0.025364025773045206
|
| 22 | GO:0015893
|
drug transport
|
3
|
0.038762428837432084
|
| 23 | GO:0009891
GO:0009058 GO:0009889 GO:0042107 GO:0006412 GO:0042089 GO:0009059 GO:0042035 GO:0031326 GO:0045727 GO:0044249 GO:0051247 GO:0051246 GO:0006417 GO:0001816 GO:0031328 |
positive regulation of biosynthetic process
biosynthetic process regulation of biosynthetic process cytokine metabolic process translation cytokine biosynthetic process macromolecule biosynthetic process regulation of cytokine biosynthetic process regulation of cellular biosynthetic process positive regulation of protein biosynthetic process cellular biosynthetic process positive regulation of protein metabolic process regulation of protein metabolic process regulation of translation cytokine production positive regulation of cellular biosynthetic process |
4
2 3 5 4 3 3 4 4 5 3 4 3 4 2 5 |
7.45107220179815E-4
0.006462528377838672 9.665182739872952E-6 1.1423064623296648E-7 9.508078869576904E-4 1.911649515521762E-5 5.336572236452941E-4 0.01404497945978387 2.0188720827054662E-5 0.002344577027473794 1.7982587395654726E-4 0.0011225434627230987 5.207986599532932E-5 0.0025050849070753015 1.121729097628808E-7 5.110778629842067E-4 |
| 24 | GO:0048869
|
cellular developmental process
|
2
|
0.0066254902918166355
|
| 25 | GO:0051704
|
multi-organism process
|
1
|
6.726060851859962E-4
|
| 26 | GO:0060089
|
molecular transducer activity
|
1
|
2.2020146251695765E-12
|
| 27 | GO:0003727
|
single-stranded RNA binding
|
4
|
0.02624245642010032
|
| 28 | GO:0007154
|
cell communication
|
2
|
8.986793966920836E-4
|
| 29 | GO:0009611
GO:0009605 GO:0006954 GO:0006952 |
response to wounding
response to external stimulus inflammatory response defense response |
3
2 3 2 |
4.108285886567157E-4
8.016847394961193E-4 0.006414951517447036 2.5334759188098423E-4 |
| 30 | GO:0035197
|
siRNA binding
|
4
|
4.038712509745297E-4
|
E coli
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0030099
|
myeloid cell differentiation
|
4
|
0.021141317648050613
|
| 2 | GO:0050896
|
response to stimulus
|
1
|
3.095060011748832E-6
|
| 3 | GO:0045087
|
innate immune response
|
3
|
0.010505802693919679
|
| 4 | GO:0032501
|
multicellular organismal process
|
1
|
0.008580803065363652
|
| 5 | GO:0060089
|
molecular transducer activity
|
1
|
2.491721835956637E-6
|
| 6 | GO:0001871
|
pattern binding
|
2
|
8.056035546613929E-4
|
| 7 | GO:0008329
|
pattern recognition receptor activity
|
4
|
0.027643200645646515
|
| 8 | GO:0006952
|
defense response
|
2
|
2.7506377930181685E-4
|
| 9 | GO:0031325
|
positive regulation of cellular metabolic process
|
4
|
8.000932591925511E-5
|
| 10 | GO:0017171
|
serine hydrolase activity
|
3
|
0.007363045794356372
|
| 11 | GO:0009893
GO:0048522 GO:0019222 |
positive regulation of metabolic process
positive regulation of cellular process regulation of metabolic process |
3
3 2 |
1.8484475597897824E-5
8.018829232470146E-4 0.03478910225343167 |
| 12 | GO:0016020
|
membrane
|
2
|
3.720713833521685E-4
|
| 13 | GO:0009611
GO:0009605 GO:0006950 |
response to wounding
response to external stimulus response to stress |
3
2 2 |
8.918140830279325E-5
1.579620135679492E-4 0.02801948556658393 |
| 14 | GO:0045357
|
regulation of interferon-beta biosynthetic
process
|
5
|
0.04626506173157813
|
| 15 | GO:0019538
GO:0044260 |
protein metabolic process
cellular macromolecule metabolic process |
3
3 |
0.001163040760007565
5.035456683697488E-4 |
| 16 | GO:0009607
GO:0051704 |
response to biotic stimulus
multi-organism process |
2
1 |
0.0361452536169447
9.60033871943401E-5 |
| 17 | GO:0043235
|
receptor complex
|
3
|
0.029601166780857124
|
| 18 | GO:0009891
GO:0009058 GO:0009889 GO:0042107 GO:0006412 GO:0009059 GO:0042089 GO:0042035 GO:0031326 GO:0045727 GO:0044249 GO:0006417 GO:0001816 GO:0031328 |
positive regulation of biosynthetic process
biosynthetic process regulation of biosynthetic process cytokine metabolic process translation macromolecule biosynthetic process cytokine biosynthetic process regulation of cytokine biosynthetic process regulation of cellular biosynthetic process positive regulation of protein biosynthetic process cellular biosynthetic process regulation of translation cytokine production positive regulation of cellular biosynthetic process |
4
2 3 5 4 3 3 4 4 5 3 4 2 5 |
8.76245529010482E-4
0.026481402009545 1.0911597708589599E-5 2.730782764672828E-6 0.021964022293499447 0.0021254881109458836 1.7265395624350393E-5 0.01912072363373158 7.779841529110235E-6 0.015670188069172468 0.001077827505481354 0.01647202332754347 8.970651490353205E-6 1.792175020822088E-4 |
| 19 | GO:0006955
|
immune response
|
2
|
0.0013953438269261743
|
| 20 | GO:0002376
|
immune system process
|
1
|
1.353870115778336E-9
|
| 21 | GO:0007243
GO:0007249 |
protein kinase cascade
I-kappaB kinase/NF-kappaB cascade |
5
6 |
0.029962485798989053
0.026877742346014494 |
| 22 | GO:0051247
GO:0051246 |
positive regulation of protein metabolic process
regulation of protein metabolic process |
4
3 |
1.0331376614448873E-4
1.6759414389949065E-5 |
| 23 | GO:0003727
|
single-stranded RNA binding
|
4
|
0.031004649001018236
|
| 24 | GO:0051239
|
regulation of multicellular organismal process
|
2
|
0.04591141608801821
|
| 25 | GO:0048518
|
positive regulation of biological process
|
3
|
7.9565960904551E-5
|
| 26 | GO:0031982
|
vesicle
|
2
|
0.03341897436665866
|
| 27 | GO:0035197
|
siRNA binding
|
4
|
4.7875190485996573E-4
|
Epstein Bar virus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0005515
|
protein binding
|
2
|
0.0027736433446581446
|
| 2 | GO:0044421
|
extracellular region part
|
1
|
0.003802043338882889
|
| 3 | GO:0005178
|
integrin binding
|
4
|
0.013124107133708285
|
| 4 | GO:0031012
|
extracellular matrix
|
1
|
0.002090411916772338
|
HIV
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0044445
|
cytosolic part
|
4
|
0.018513408374950035
|
| 2 | GO:0031967
GO:0031975 |
organelle envelope
envelope |
2
1 |
7.490637307780582E-5
2.622417829847284E-6 |
| 3 | GO:0001773
|
myeloid dendritic cell activation
|
4
|
0.03446227882049475
|
| 4 | GO:0043067
|
regulation of programmed cell death
|
3
|
1.2319339519145392E-6
|
| 5 | GO:0042089
|
cytokine biosynthetic process
|
3
|
0.009411248164238358
|
| 6 | GO:0008537
GO:0008538 |
proteasome activator complex
proteasome activator activity |
3
3 |
0.01930042293483195
0.0015773434521996227 |
| 7 | GO:0006366
|
transcription from RNA polymerase II promoter
|
6
|
6.619214907847111E-6
|
| 8 | GO:0018193
|
peptidyl-amino acid modification
|
6
|
0.007164791026995074
|
| 9 | GO:0009897
|
external side of plasma membrane
|
3
|
0.033584902562657476
|
| 10 | GO:0002263
|
cell activation during immune response
|
3
|
0.03671450116435842
|
| 11 | GO:0006352
|
transcription initiation
|
5
|
6.704559651501689E-4
|
| 12 | GO:0030522
|
intracellular receptor-mediated signaling pathway
|
5
|
0.04082105340692615
|
| 13 | GO:0045840
|
positive regulation of mitosis
|
5
|
0.006717420566776632
|
| 14 | GO:0005942
|
phosphoinositide 3-kinase complex
|
3
|
0.010235746609277311
|
| 15 | GO:0017038
|
protein import
|
4
|
0.0016286875148093358
|
| 16 | GO:0005143
|
interleukin-12 receptor binding
|
5
|
0.047660373107215014
|
| 17 | GO:0051707
|
response to other organism
|
2
|
0.045447870497937214
|
| 18 | GO:0051649
|
establishment of cellular localization
|
2
|
6.676922148684803E-8
|
| 19 | GO:0051325
|
interphase
|
4
|
0.006423235154951455
|
| 20 | GO:0009893
|
positive regulation of metabolic process
|
3
|
0.0026319878345941786
|
| 21 | GO:0006259
|
DNA metabolic process
|
4
|
1.2351766177298105E-5
|
| 22 | GO:0032991
|
macromolecular complex
|
1
|
2.5724815469915037E-53
|
| 23 | GO:0043069
|
negative regulation of programmed cell death
|
4
|
3.915640373443446E-6
|
| 24 | GO:0044428
|
nuclear part
|
3
|
9.013748726767265E-15
|
| 25 | GO:0043233
GO:0031974 |
organelle lumen
membrane-enclosed lumen |
2
1 |
4.0761200521287377E-4
3.931474567368162E-12 |
| 26 | GO:0005665
|
DNA-directed RNA polymerase II, core complex
|
4
|
0.010351101890114634
|
| 27 | GO:0051174
GO:0019220 |
regulation of phosphorus metabolic process
regulation of phosphate metabolic process |
4
5 |
0.032522564345547206
0.03433866750386168 |
| 28 | GO:0006139
|
nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
|
3
|
1.3238316389057572E-6
|
| 29 | GO:0007049
|
cell cycle
|
2
|
0.01602148040301333
|
| 30 | GO:0008243
|
plasminogen activator activity
|
6
|
0.006228724827754557
|
| 31 | GO:0009987
|
cellular process
|
1
|
0.0189408798668168
|
| 32 | GO:0016032
|
viral reproduction
|
1
|
1.5546030215224355E-6
|
| 33 | GO:0005643
|
nuclear pore
|
3
|
2.8277663396950895E-9
|
| 34 | GO:0008601
|
protein phosphatase type 2A regulator activity
|
4
|
0.002200963280976202
|
| 35 | GO:0016849
GO:0009190 |
phosphorus-oxygen lyase activity
cyclic nucleotide biosynthetic process |
3
5 |
6.380035411474781E-5
0.003986963273490198 |
| 36 | GO:0043231
|
intracellular membrane-bound organelle
|
3
|
3.398422448955904E-5
|
| 37 | GO:0030163
|
protein catabolic process
|
4
|
1.5528636395216287E-4
|
| 38 | GO:0008152
|
metabolic process
|
1
|
3.4520610745589756E-7
|
| 39 | GO:0005694
|
chromosome
|
4
|
8.772333869949864E-14
|
| 40 | GO:0009986
|
cell surface
|
2
|
0.007149069569204865
|
| 41 | GO:0043227
|
membrane-bound organelle
|
2
|
1.8963656178198804E-5
|
| 42 | GO:0000159
|
protein phosphatase type 2A complex
|
3
|
1.2429645458706503E-9
|
| 43 | GO:0051329
|
interphase of mitotic cell cycle
|
4
|
0.007570224470934928
|
| 44 | GO:0003702
|
RNA polymerase II transcription factor activity
|
2
|
0.027172676846382166
|
| 45 | GO:0016779
|
nucleotidyltransferase activity
|
4
|
5.279599475436457E-5
|
| 46 | GO:0005838
|
proteasome regulatory particle (sensu Eukaryota)
|
3
|
1.6393061317112775E-7
|
| 47 | GO:0044451
|
nucleoplasm part
|
4
|
0.006557756472882858
|
| 48 | GO:0048522
|
positive regulation of cellular process
|
3
|
1.6972173362941985E-6
|
| 49 | GO:0003712
|
transcription cofactor activity
|
2
|
0.03964684503171723
|
| 50 | GO:0042578
|
phosphoric ester hydrolase activity
|
4
|
1.6126856546781018E-6
|
| 51 | GO:0044237
|
cellular metabolic process
|
2
|
6.584754014121545E-8
|
| 52 | GO:0006816
|
calcium ion transport
|
6
|
0.004828947145639043
|
| 53 | GO:0007154
|
cell communication
|
2
|
0.015444214558364394
|
| 54 | GO:0055082
|
cellular chemical homeostasis
|
3
|
0.007869452499605061
|
| 55 | GO:0009607
|
response to biotic stimulus
|
2
|
0.004637293497386208
|
| 56 | GO:0016684
GO:0004602 |
oxidoreductase activity, acting on peroxide as
acceptor
glutathione peroxidase activity |
3
3 |
0.0057734699117661025
0.0 |
| 57 | GO:0016563
|
transcription activator activity
|
2
|
0.007248919168495554
|
| 58 | GO:0046870
|
cadmium ion binding
|
5
|
0.0
|
| 59 | GO:0016209
|
antioxidant activity
|
1
|
0.00788181605749617
|
| 60 | GO:0002504
GO:0042613 |
antigen processing and presentation of peptide or
polysaccharide antigen via MHC class II
MHC class II protein complex |
3
4 |
0.00855995610142542
0.0047999750942043055 |
| 61 | GO:0005515
|
protein binding
|
2
|
5.806284127286213E-6
|
| 62 | GO:0042127
|
regulation of cell proliferation
|
3
|
0.028872604097572214
|
| 63 | GO:0003676
|
nucleic acid binding
|
2
|
2.106581902422543E-5
|
| 64 | GO:0022415
|
viral reproductive process
|
2
|
2.0046525351511517E-6
|
| 65 | GO:0048869
|
cellular developmental process
|
2
|
0.0077854113301486
|
| 66 | GO:0048525
|
negative regulation of viral life cycle
|
3
|
0.0023128031053741985
|
| 67 | GO:0000805
GO:0001740 GO:0007549 |
X chromosome
Barr body dosage compensation |
6
7 4 |
0.0
0.0 0.0 |
| 68 | GO:0005125
|
cytokine activity
|
4
|
0.002587472408216157
|
| 69 | GO:0032943
|
mononuclear cell proliferation
|
3
|
0.00659519172439094
|
| 70 | GO:0031323
|
regulation of cellular metabolic process
|
3
|
0.015987750585934966
|
| 71 | GO:0019992
|
diacylglycerol binding
|
3
|
0.04536068915213042
|
| 72 | GO:0005634
|
nucleus
|
4
|
2.007630818046409E-26
|
| 73 | GO:0003899
|
DNA-directed RNA polymerase activity
|
5
|
4.670388618405737E-4
|
| 74 | GO:0015085
GO:0008095 |
calcium ion transmembrane transporter activity
inositol-1,4,5-triphosphate receptor activity |
6
4 |
0.007789208539236338
0.022917766856666712 |
| 75 | GO:0002521
|
leukocyte differentiation
|
4
|
6.855003035705327E-4
|
| 76 | GO:0043283
|
biopolymer metabolic process
|
3
|
2.1464296985050908E-5
|
| 77 | GO:0048518
|
positive regulation of biological process
|
3
|
3.711285791843268E-5
|
| 78 | GO:0043256
|
laminin complex
|
2
|
0.0027901237687010102
|
| 79 | GO:0008094
|
DNA-dependent ATPase activity
|
9
|
0.04903768872816163
|
| 80 | GO:0000785
|
chromatin
|
4
|
1.0721930497360549E-5
|
| 81 | GO:0051276
|
chromosome organization and biogenesis
|
4
|
1.922604292691588E-5
|
| 82 | GO:0030528
|
transcription regulator activity
|
1
|
3.308796290501363E-8
|
| 83 | GO:0005654
|
nucleoplasm
|
4
|
0.007826223307635521
|
| 84 | GO:0006605
|
protein targeting
|
5
|
9.993589668091421E-7
|
| 85 | GO:0031325
|
positive regulation of cellular metabolic process
|
4
|
0.003926970743594167
|
| 86 | GO:0004722
|
protein serine/threonine phosphatase activity
|
7
|
0.0065663955799549
|
| 87 | GO:0017056
|
structural constituent of nuclear pore
|
2
|
0.037917360637807124
|
| 88 | GO:0005666
|
DNA-directed RNA polymerase III complex
|
5
|
0.004622607498280469
|
| 89 | GO:0002376
|
immune system process
|
1
|
2.637828158882524E-14
|
| 90 | GO:0065007
|
biological regulation
|
1
|
1.9617319990591592E-6
|
| 91 | GO:0032395
|
MHC class II receptor activity
|
5
|
0.004628526920212722
|
| 92 | GO:0009187
|
cyclic nucleotide metabolic process
|
5
|
1.8268393016377448E-6
|
| 93 | GO:0042101
|
T cell receptor complex
|
4
|
0.01025869059137944
|
| 94 | GO:0016251
|
general RNA polymerase II transcription factor
activity
|
3
|
0.0014355405170470392
|
| 95 | GO:0043543
|
protein amino acid acylation
|
6
|
0.0324632105871575
|
| 96 | GO:0015695
GO:0015101 |
organic cation transport
organic cation transmembrane transporter activity |
5
6 |
0.04497949590552976
0.016273789104807004 |
| 97 | GO:0050793
|
regulation of developmental process
|
2
|
0.020669817762210333
|
| 98 | GO:0005669
|
transcription factor TFIID complex
|
4
|
0.03729260916920707
|
| 99 | GO:0044424
|
intracellular part
|
2
|
3.965847265902868E-6
|
| 100 | GO:0050792
|
regulation of viral life cycle
|
2
|
1.1236341333189085E-5
|
| 101 | GO:0004016
GO:0009975 |
adenylate cyclase activity
cyclase activity |
3
2 |
0.007122275931241079
0.0034124728177553636 |
| 102 | GO:0004697
GO:0001565 |
protein kinase C activity
phorbol ester receptor activity |
5
4 |
4.1954095897561646E-6
1.76532595524877E-7 |
| 103 | GO:0051603
GO:0044257 |
proteolysis involved in cellular protein
catabolic process
cellular protein catabolic process |
6
5 |
6.656381756119834E-4
0.008416633664304486 |
| 104 | GO:0045941
|
positive regulation of transcription
|
6
|
0.040478455630855684
|
| 105 | GO:0008283
|
cell proliferation
|
2
|
0.0014392484345565114
|
| 106 | GO:0006368
|
RNA elongation from RNA polymerase II promoter
|
6
|
0.01980932230337366
|
| 107 | GO:0044238
|
primary metabolic process
|
2
|
4.537392889510609E-7
|
| 108 | GO:0006354
|
RNA elongation
|
5
|
1.8285156525742574E-6
|
| 109 | GO:0050794
|
regulation of cellular process
|
2
|
3.0994740211369116E-5
|
| 110 | GO:0015026
|
coreceptor activity
|
4
|
0.016187572748656304
|
| 111 | GO:0046930
|
pore complex
|
5
|
1.9707887356935732E-23
|
| 112 | GO:0006928
GO:0051674 |
cell motility
localization of cell |
2
2 |
0.007686391858213563
0.0020200118946761677 |
| 113 | GO:0019208
|
phosphatase regulator activity
|
2
|
7.534923630057866E-4
|
| 114 | GO:0006334
GO:0000786 GO:0031497 |
nucleosome assembly
nucleosome chromatin assembly |
5
3 4 |
0.002031085537720203
5.760881527006704E-22 1.682167578194177E-9 |
| 115 | GO:0022402
|
cell cycle process
|
2
|
0.012723834491265169
|
| 116 | GO:0004428
GO:0001727 GO:0035004 |
inositol or phosphatidylinositol kinase activity
lipid kinase activity phosphoinositide 3-kinase activity |
5
5 6 |
0.009518354079505988
0.0018045565938703775 2.2775424984045544E-4 |
| 117 | GO:0031594
|
neuromuscular junction
|
2
|
0.005162214021676178
|
| 118 | GO:0008134
|
transcription factor binding
|
3
|
5.129429355687688E-4
|
| 119 | GO:0000502
|
proteasome complex (sensu Eukaryota)
|
3
|
2.829286859223892E-29
|
| 120 | GO:0001772
|
immunological synapse
|
4
|
0.015241111440294558
|
| 121 | GO:0008287
|
protein serine/threonine phosphatase complex
|
2
|
1.086169229343579E-9
|
| 122 | GO:0001637
|
G-protein chemoattractant receptor activity
|
5
|
6.709722576098636E-4
|
| 123 | GO:0005487
|
nucleocytoplasmic transporter activity
|
2
|
0.001048996885173539
|
| 124 | GO:0045935
|
positive regulation of nucleobase, nucleoside,
nucleotide and nucleic acid metabolic process
|
5
|
0.022402087297625117
|
| 125 | GO:0004298
|
threonine endopeptidase activity
|
5
|
4.4353292051715344E-13
|
| 126 | GO:0005955
|
calcineurin complex
|
3
|
0.029608551064941813
|
| 127 | GO:0045995
|
regulation of embryonic development
|
3
|
0.011825979956249618
|
| 128 | GO:0005663
|
DNA replication factor C complex
|
3
|
0.016480961646415788
|
| 129 | GO:0006383
|
transcription from RNA polymerase III promoter
|
6
|
1.9893180617492124E-5
|
| 130 | GO:0004112
|
cyclic-nucleotide phosphodiesterase activity
|
6
|
2.3425348201504543E-5
|
| 131 | GO:0006521
GO:0033238 |
regulation of amino acid metabolic process
regulation of amine metabolic process |
5
4 |
0.002727329993455529
0.012722530616912066 |
| 132 | GO:0006323
|
DNA packaging
|
5
|
0.04978825773573464
|
| 133 | GO:0019222
|
regulation of metabolic process
|
2
|
0.009581780247258583
|
| 134 | GO:0065003
GO:0022607 |
macromolecular complex assembly
cellular component assembly |
3
3 |
3.7695101539149224E-14
8.97378904098037E-12 |
| 135 | GO:0005952
|
cAMP-dependent protein kinase complex
|
3
|
0.001474151963477961
|
| 136 | GO:0005829
|
cytosol
|
4
|
8.919223317214736E-20
|
| 137 | GO:0016772
|
transferase activity, transferring
phosphorus-containing groups
|
3
|
3.923129513035606E-6
|
| 138 | GO:0009057
|
macromolecule catabolic process
|
3
|
0.02461200004125425
|
| 139 | GO:0042330
|
taxis
|
3
|
3.706164118326416E-5
|
| 140 | GO:0005839
|
proteasome core complex (sensu Eukaryota)
|
3
|
3.3802159073076125E-14
|
| 141 | GO:0006325
|
establishment and/or maintenance of chromatin
architecture
|
6
|
0.014885044686635537
|
| 142 | GO:0043170
|
macromolecule metabolic process
|
2
|
3.727004670986889E-6
|
| 143 | GO:0005853
|
eukaryotic translation elongation factor 1
complex
|
3
|
0.04776320036642925
|
| 144 | GO:0004175
|
endopeptidase activity
|
4
|
0.02230401368617442
|
| 145 | GO:0005262
|
calcium channel activity
|
7
|
0.0452462740827586
|
| 146 | GO:0004115
|
3',5'-cyclic-AMP phosphodiesterase activity
|
8
|
0.0
|
| 147 | GO:0030880
|
RNA polymerase complex
|
3
|
2.314430998586718E-10
|
| 148 | GO:0035005
|
phosphatidylinositol-4-phosphate 3-kinase
activity
|
7
|
0.0
|
| 149 | GO:0005667
|
transcription factor complex
|
3
|
0.001375351263889828
|
| 150 | GO:0008081
|
phosphoric diester hydrolase activity
|
5
|
4.834195163892361E-7
|
| 151 | GO:0043285
|
biopolymer catabolic process
|
4
|
0.007231318105195548
|
| 152 | GO:0044446
|
intracellular organelle part
|
2
|
7.696541306409211E-9
|
| 153 | GO:0044256
|
protein digestion
|
3
|
0.04063716713979854
|
| 154 | GO:0016410
|
N-acyltransferase activity
|
6
|
2.5809960999204854E-4
|
| 155 | GO:0015630
|
microtubule cytoskeleton
|
5
|
0.006373424882200861
|
| 156 | GO:0065004
|
protein-DNA complex assembly
|
4
|
6.0765218787511424E-12
|
| 157 | GO:0051704
|
multi-organism process
|
1
|
2.956236812425887E-4
|
| 158 | GO:0005126
|
hematopoietin/interferon-class (D200-domain)
cytokine receptor binding
|
5
|
0.04709619205522375
|
| 159 | GO:0003824
|
catalytic activity
|
1
|
0.017249187434931736
|
| 160 | GO:0004693
|
cyclin-dependent protein kinase activity
|
7
|
0.002985830508411267
|
| 161 | GO:0051169
|
nuclear transport
|
4
|
8.731991740695537E-7
|
| 162 | GO:0005635
|
nuclear envelope
|
3
|
8.37958883347732E-10
|
| 163 | GO:0005622
|
intracellular
|
2
|
0.00479600334371158
|
| 164 | GO:0019725
|
cellular homeostasis
|
2
|
0.003288787849080304
|
| 165 | GO:0044421
|
extracellular region part
|
1
|
0.004809482742187138
|
| 166 | GO:0030155
|
regulation of cell adhesion
|
3
|
0.022397791666589326
|
| 167 | GO:0043234
|
protein complex
|
2
|
3.3690530090046226E-9
|
| 168 | GO:0002520
GO:0048534 |
immune system development
hemopoietic or lymphoid organ development |
2
3 |
0.01619533590595833
2.469454194752287E-4 |
| 169 | GO:0005048
GO:0008139 |
signal sequence binding
nuclear localization sequence binding |
3
4 |
0.02237362662271096
0.00482793927021712 |
| 170 | GO:0007172
|
signal complex assembly
|
6
|
0.018860521810515084
|
| 171 | GO:0031965
|
nuclear membrane
|
3
|
6.414313027503023E-13
|
| 172 | GO:0005102
|
receptor binding
|
3
|
0.007776722752941873
|
| 173 | GO:0003709
GO:0000127 |
RNA polymerase III transcription factor activity
transcription factor TFIIIC complex |
2
4 |
0.028873918585581148
0.039847904339042825 |
| 174 | GO:0005488
|
binding
|
1
|
1.024260746476116E-4
|
| 175 | GO:0006333
|
chromatin assembly or disassembly
|
7
|
9.888657563234558E-8
|
| 176 | GO:0001730
|
2'-5'-oligoadenylate synthetase activity
|
5
|
0.0
|
| 177 | GO:0019955
|
cytokine binding
|
3
|
0.043449020531545965
|
| 178 | GO:0001763
|
morphogenesis of a branching structure
|
3
|
0.012051143554934684
|
| 179 | GO:0044453
|
nuclear membrane part
|
3
|
1.0427797840036926E-20
|
| 180 | GO:0046907
|
intracellular transport
|
3
|
1.2969349542140766E-10
|
| 181 | GO:0012505
|
endomembrane system
|
3
|
6.015665178327625E-9
|
| 182 | GO:0044427
|
chromosomal part
|
3
|
1.5886690288977419E-6
|
| 183 | GO:0016265
GO:0008219 |
death
cell death |
2
3 |
1.3618417768415115E-9
1.8871212939589094E-6 |
| 184 | GO:0005507
|
copper ion binding
|
5
|
4.054178088308144E-5
|
| 185 | GO:0003677
|
DNA binding
|
3
|
0.004652772527933156
|
| 186 | GO:0003713
|
transcription coactivator activity
|
3
|
0.005713858728966972
|
| 187 | GO:0015931
GO:0051236 GO:0006403 |
nucleobase, nucleoside, nucleotide and nucleic
acid transport
establishment of RNA localization RNA localization |
3
2 3 |
2.830106625878819E-15
1.4894530410007519E-16 6.841396627889234E-15 |
| 188 | GO:0050730
|
regulation of peptidyl-tyrosine phosphorylation
|
4
|
0.010158542047650801
|
| 189 | GO:0006468
|
protein amino acid phosphorylation
|
6
|
5.840891631871994E-5
|
| 190 | GO:0048468
|
cell development
|
2
|
2.0699667564579576E-5
|
| 191 | GO:0043623
|
cellular protein complex assembly
|
5
|
0.01483712081037977
|
| 192 | GO:0044422
|
organelle part
|
1
|
4.025787023991305E-12
|
| 193 | GO:0015276
GO:0022834 |
ligand-gated ion channel activity
ligand-gated channel activity |
6
6 |
0.04187007765696687
0.037188667694798394 |
| 194 | GO:0016043
|
cellular component organization and biogenesis
|
2
|
2.14392693950314E-6
|
| 195 | GO:0001816
|
cytokine production
|
2
|
0.01817390448013248
|
| 196 | GO:0003711
|
transcription elongation regulator activity
|
2
|
3.546832340116421E-4
|
| 197 | GO:0004652
|
polynucleotide adenylyltransferase activity
|
5
|
0.0
|
| 198 | GO:0001775
|
cell activation
|
2
|
9.762862900555555E-5
|
| 199 | GO:0006955
|
immune response
|
2
|
3.0509095137318774E-4
|
| 200 | GO:0016591
|
DNA-directed RNA polymerase II, holoenzyme
|
3
|
3.239493945393881E-7
|
| 201 | GO:0050896
|
response to stimulus
|
1
|
3.499165655062307E-14
|
Hepatitis
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0005515
|
protein binding
|
2
|
0.035902921330711476
|
| 2 | GO:0048869
|
cellular developmental process
|
2
|
0.016110227582289218
|
| 3 | GO:0008199
|
ferric iron binding
|
6
|
0.01286332090696209
|
| 4 | GO:0050896
|
response to stimulus
|
1
|
0.0014826408560081787
|
| 5 | GO:0032502
|
developmental process
|
1
|
0.03898100909221551
|
| 6 | GO:0048468
|
cell development
|
2
|
0.018362394792016203
|
| 7 | GO:0051704
|
multi-organism process
|
1
|
0.03643810989681612
|
| 8 | GO:0065003
|
macromolecular complex assembly
|
3
|
0.014553146473211579
|
| 9 | GO:0016032
|
viral reproduction
|
1
|
0.01529691365924926
|
Herpesvirus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0051704
|
multi-organism process
|
1
|
0.03488533226437376
|
| 2 | GO:0005515
|
protein binding
|
2
|
4.966921226045673E-4
|
| 3 | GO:0044237
|
cellular metabolic process
|
2
|
0.02616203455822793
|
| 4 | GO:0022414
|
reproductive process
|
1
|
0.0070560637436856526
|
| 5 | GO:0006464
|
protein modification process
|
5
|
0.020813611618370753
|
| 6 | GO:0031974
|
membrane-enclosed lumen
|
1
|
0.008141623344150636
|
| 7 | GO:0001948
|
glycoprotein binding
|
3
|
0.025971898482825
|
| 8 | GO:0000003
|
reproduction
|
1
|
0.020772594391009192
|
| 9 | GO:0001816
|
cytokine production
|
2
|
0.03638656326523442
|
| 10 | GO:0016032
GO:0022415 |
viral reproduction
viral reproductive process |
1
2 |
1.1369562244119914E-4
0.008161975754289537 |
| 11 | GO:0032991
|
macromolecular complex
|
1
|
0.049176133051778474
|
| 12 | GO:0007049
|
cell cycle
|
2
|
0.03621471680496795
|
| 13 | GO:0060089
|
molecular transducer activity
|
1
|
0.016978595730225463
|
| 14 | GO:0016874
GO:0008639 |
ligase activity
small protein conjugating enzyme activity |
2
2 |
0.03441757214771694
0.0017115000447721499 |
| 15 | GO:0006955
|
immune response
|
2
|
0.023515027570534985
|
| 16 | GO:0005634
|
nucleus
|
4
|
0.00762842033023731
|
| 17 | GO:0031323
|
regulation of cellular metabolic process
|
3
|
0.006356894835726109
|
| 18 | GO:0065007
|
biological regulation
|
1
|
0.001887400757379695
|
| 19 | GO:0019222
|
regulation of metabolic process
|
2
|
0.0016235054611999143
|
| 20 | GO:0000119
|
mediator complex
|
3
|
0.046711338834267355
|
| 21 | GO:0008152
GO:0043170 |
metabolic process
macromolecule metabolic process |
1
2 |
0.03682564050876846
0.017224975712103425 |
| 22 | GO:0050896
|
response to stimulus
|
1
|
0.008663945597982886
|
| 23 | GO:0002376
|
immune system process
|
1
|
6.440863644327338E-4
|
| 24 | GO:0022402
|
cell cycle process
|
2
|
0.03705771334546753
|
| 25 | GO:0051239
|
regulation of multicellular organismal process
|
2
|
0.006807995865170479
|
| 26 | GO:0007250
|
activation of NF-kappaB-inducing kinase
|
7
|
0.024193383633846925
|
| 27 | GO:0001775
|
cell activation
|
2
|
0.02571096424016195
|
| 28 | GO:0044419
|
interspecies interaction between organisms
|
2
|
0.035205332777513386
|
| 29 | GO:0050794
|
regulation of cellular process
|
2
|
0.00143001206863195
|
| 30 | GO:0050850
GO:0050848 |
positive regulation of calcium-mediated signaling
regulation of calcium-mediated signaling |
5
4 |
0.03660127613993211
0.019223352439317214 |
| 31 | GO:0002768
GO:0002764 |
immune response-regulating cell surface receptor
signaling pathway
immune response-regulating signal transduction |
5
4 |
0.006456350734510199
0.002053828202912388 |
Influenza
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0030880
|
RNA polymerase complex
|
3
|
9.741819162180479E-13
|
| 2 | GO:0005674
|
transcription factor TFIIF complex
|
4
|
0.03227007308495286
|
| 3 | GO:0006139
|
nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
|
3
|
7.512243533418281E-17
|
| 4 | GO:0030530
|
heterogeneous nuclear ribonucleoprotein complex
|
3
|
2.3496736575492734E-13
|
| 5 | GO:0016591
|
DNA-directed RNA polymerase II, holoenzyme
|
3
|
2.3630231258606062E-8
|
| 6 | GO:0044424
|
intracellular part
|
2
|
1.0796121129134154E-7
|
| 7 | GO:0007052
|
mitotic spindle organization and biogenesis
|
3
|
0.017991123963320945
|
| 8 | GO:0003899
GO:0016779 |
DNA-directed RNA polymerase activity
nucleotidyltransferase activity |
5
4 |
1.2504039470683916E-4
3.138583862299256E-8 |
| 9 | GO:0008380
|
RNA splicing
|
6
|
3.1249023278827673E-4
|
| 10 | GO:0006356
|
regulation of transcription from RNA polymerase I
promoter
|
7
|
0.005546313468028088
|
| 11 | GO:0005622
|
intracellular
|
2
|
3.860344161773861E-7
|
| 12 | GO:0032991
|
macromolecular complex
|
1
|
1.4625331816703293E-22
|
| 13 | GO:0016740
GO:0016772 |
transferase activity
transferase activity, transferring phosphorus-containing groups |
2
3 |
0.0017662360030065289
0.020683693024482523 |
| 14 | GO:0033036
|
macromolecule localization
|
2
|
0.0014080639398689253
|
| 15 | GO:0016265
|
death
|
2
|
0.020851356321599387
|
| 16 | GO:0000166
|
nucleotide binding
|
2
|
3.039242611550856E-8
|
| 17 | GO:0043227
GO:0043229 GO:0043226 GO:0043231 |
membrane-bound organelle
intracellular organelle organelle intracellular membrane-bound organelle |
2
2 1 3 |
1.6134087225066742E-4
0.015125586366115697 8.968269525508705E-10 1.5770558483245328E-4 |
| 18 | GO:0003676
|
nucleic acid binding
|
2
|
4.9457270601729874E-23
|
| 19 | GO:0005681
|
spliceosome
|
3
|
1.3097307983745726E-10
|
| 20 | GO:0006366
|
transcription from RNA polymerase II promoter
|
6
|
0.02127097084798868
|
| 21 | GO:0005665
|
DNA-directed RNA polymerase II, core complex
|
4
|
4.280046159159468E-9
|
| 22 | GO:0022613
GO:0022618 |
ribonucleoprotein complex biogenesis and assembly
protein-RNA complex assembly |
3
4 |
7.960939992020907E-4
0.003179553221821262 |
| 23 | GO:0005488
|
binding
|
1
|
5.530323511355351E-5
|
| 24 | GO:0043170
|
macromolecule metabolic process
|
2
|
3.900216737521371E-4
|
| 25 | GO:0017038
|
protein import
|
4
|
0.03380077746789344
|
| 26 | GO:0006396
|
RNA processing
|
5
|
2.9746856781790626E-18
|
| 27 | GO:0046930
GO:0012505 |
pore complex
endomembrane system |
5
3 |
2.3629595797483336E-4
0.008628220738538387 |
| 28 | GO:0031974
|
membrane-enclosed lumen
|
1
|
4.4634392300951515E-7
|
| 29 | GO:0003723
|
RNA binding
|
3
|
2.95877053743237E-17
|
| 30 | GO:0044237
GO:0008152 |
cellular metabolic process
metabolic process |
2
1 |
2.7746171781403544E-10
6.306447363998246E-11 |
| 31 | GO:0043283
|
biopolymer metabolic process
|
3
|
3.57114471299694E-5
|
| 32 | GO:0030532
|
small nuclear ribonucleoprotein complex
|
3
|
2.569699866798967E-4
|
| 33 | GO:0016070
|
RNA metabolic process
|
4
|
2.888345883780362E-13
|
| 34 | GO:0005515
|
protein binding
|
2
|
0.03669621887228581
|
| 35 | GO:0044422
GO:0044446 |
organelle part
intracellular organelle part |
1
2 |
1.1362293777855806E-18
3.915996087903833E-12 |
| 36 | GO:0009987
|
cellular process
|
1
|
0.001089059017379111
|
| 37 | GO:0006397
|
mRNA processing
|
6
|
1.5971288637523447E-4
|
| 38 | GO:0046907
|
intracellular transport
|
3
|
0.017097690010821995
|
| 39 | GO:0043623
|
cellular protein complex assembly
|
5
|
0.036653550874055425
|
| 40 | GO:0016071
|
mRNA metabolic process
|
5
|
8.06400150416125E-21
|
| 41 | GO:0022607
|
cellular component assembly
|
3
|
0.0067049903722556075
|
| 42 | GO:0030529
|
ribonucleoprotein complex
|
2
|
1.6397704224790397E-22
|
| 43 | GO:0051169
|
nuclear transport
|
4
|
5.247235794789473E-4
|
| 44 | GO:0051236
GO:0015931 GO:0006403 |
establishment of RNA localization
nucleobase, nucleoside, nucleotide and nucleic acid transport RNA localization |
2
3 3 |
9.771280004608309E-7
1.8162805195112344E-6 2.0266938831680159E-4 |
| 45 | GO:0006376
|
mRNA splice site selection
|
2
|
5.330430977739061E-5
|
| 46 | GO:0005634
|
nucleus
|
4
|
1.265402146974521E-10
|
| 47 | GO:0044428
|
nuclear part
|
3
|
7.13291035943496E-19
|
Measles virus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0051082
|
unfolded protein binding
|
3
|
8.676438777237459E-4
|
Multibacteria
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0050896
|
response to stimulus
|
1
|
1.2777201651708606E-6
|
| 2 | GO:0019222
|
regulation of metabolic process
|
2
|
3.829337976397748E-4
|
| 3 | GO:0002376
|
immune system process
|
1
|
1.3972807808133126E-9
|
| 4 | GO:0008329
|
pattern recognition receptor activity
|
4
|
0.03399937434780835
|
| 5 | GO:0016020
|
membrane
|
2
|
0.001024156775039508
|
| 6 | GO:0019538
|
protein metabolic process
|
3
|
0.02310920260625581
|
| 7 | GO:0051246
|
regulation of protein metabolic process
|
3
|
4.789840877847005E-7
|
| 8 | GO:0065009
|
regulation of a molecular function
|
2
|
0.04101340986720656
|
| 9 | GO:0030099
GO:0048534 |
myeloid cell differentiation
hemopoietic or lymphoid organ development |
4
3 |
0.008050935070922435
0.01554783709083149 |
| 10 | GO:0001871
|
pattern binding
|
2
|
0.012009885180437066
|
| 11 | GO:0005515
|
protein binding
|
2
|
0.012074402774496338
|
| 12 | GO:0007154
|
cell communication
|
2
|
0.0026822868438713637
|
| 13 | GO:0043552
GO:0030742 |
positive regulation of phosphoinositide 3-kinase
activity
GTP-dependent protein binding |
6
3 |
0.02270650414277914
0.006349825061394444 |
| 14 | GO:0009611
GO:0009605 GO:0006954 GO:0006952 |
response to wounding
response to external stimulus inflammatory response defense response |
3
2 3 2 |
2.9297782771294043E-4
0.0013322094623911072 0.004610008500151411 3.93069405600099E-4 |
| 15 | GO:0051247
|
positive regulation of protein metabolic process
|
4
|
0.0011333769395394976
|
| 16 | GO:0007243
GO:0007249 |
protein kinase cascade
I-kappaB kinase/NF-kappaB cascade |
5
6 |
0.031372184315166814
0.011503178845180114 |
| 17 | GO:0045357
|
regulation of interferon-beta biosynthetic
process
|
5
|
0.04488359996845085
|
| 18 | GO:0048522
GO:0031323 GO:0031325 |
positive regulation of cellular process
regulation of cellular metabolic process positive regulation of cellular metabolic process |
3
3 4 |
0.003109498909163439
0.022258546270500112 1.835460846789556E-5 |
| 19 | GO:0005121
|
Toll binding
|
4
|
0.036067552216869976
|
| 20 | GO:0009893
GO:0048518 |
positive regulation of metabolic process
positive regulation of biological process |
3
3 |
3.4990699243291107E-6
5.135563165246297E-4 |
| 21 | GO:0001530
|
lipopolysaccharide binding
|
3
|
0.030240388509797135
|
| 22 | GO:0009891
GO:0009058 GO:0009889 GO:0042107 GO:0006412 GO:0009059 GO:0042089 GO:0042035 GO:0031326 GO:0045727 GO:0044249 GO:0006417 GO:0001816 GO:0031328 |
positive regulation of biosynthetic process
biosynthetic process regulation of biosynthetic process cytokine metabolic process translation macromolecule biosynthetic process cytokine biosynthetic process regulation of cytokine biosynthetic process regulation of cellular biosynthetic process positive regulation of protein biosynthetic process cellular biosynthetic process regulation of translation cytokine production positive regulation of cellular biosynthetic process |
4
2 3 5 4 3 3 4 4 5 3 4 2 5 |
0.0025172024108871707
0.015079029436800827 5.76318392888006E-5 2.8536418231580743E-7 0.0031668088379613398 0.0013552317779156632 1.979888387116556E-5 0.017656569498293428 2.1170751365022252E-5 0.014786412790149573 4.2215499136537423E-4 0.04019260451034475 1.2608189684842316E-6 7.278170170451311E-4 |
| 23 | GO:0006955
|
immune response
|
2
|
0.0016200948491490023
|
| 24 | GO:0060089
|
molecular transducer activity
|
1
|
1.1869779255504169E-8
|
| 25 | GO:0051704
|
multi-organism process
|
1
|
0.001193292581126893
|
| 26 | GO:0003727
|
single-stranded RNA binding
|
4
|
0.031271540905791075
|
| 27 | GO:0048869
|
cellular developmental process
|
2
|
0.022085300369422738
|
| 28 | GO:0035197
|
siRNA binding
|
4
|
5.812972556946418E-4
|
Multivirus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0030880
|
RNA polymerase complex
|
3
|
1.2515868937846597E-8
|
| 2 | GO:0031975
|
envelope
|
1
|
0.04076427023523379
|
| 3 | GO:0046930
|
pore complex
|
5
|
1.156806676379921E-9
|
| 4 | GO:0015931
GO:0051236 GO:0006403 |
nucleobase, nucleoside, nucleotide and nucleic
acid transport
establishment of RNA localization RNA localization |
3
2 3 |
2.2453057365410254E-4
1.2416247907524622E-4 0.008980509563832988 |
| 5 | GO:0044446
|
intracellular organelle part
|
2
|
2.3252858383210696E-5
|
| 6 | GO:0047485
|
protein N-terminus binding
|
3
|
0.014091043623357878
|
| 7 | GO:0016043
|
cellular component organization and biogenesis
|
2
|
0.004441502781078087
|
| 8 | GO:0005622
|
intracellular
|
2
|
5.065654786814799E-7
|
| 9 | GO:0031325
|
positive regulation of cellular metabolic process
|
4
|
0.027253634770227655
|
| 10 | GO:0007049
|
cell cycle
|
2
|
6.1672868598913E-6
|
| 11 | GO:0003899
GO:0016779 |
DNA-directed RNA polymerase activity
nucleotidyltransferase activity |
5
4 |
2.7870021653601237E-4
0.014188811502051266 |
| 12 | GO:0000502
|
proteasome complex (sensu Eukaryota)
|
3
|
0.0044170241787257385
|
| 13 | GO:0006521
|
regulation of amino acid metabolic process
|
5
|
0.03116357339373297
|
| 14 | GO:0016032
GO:0022415 |
viral reproduction
viral reproductive process |
1
2 |
4.4142813976106183E-4
7.548627655082956E-4 |
| 15 | GO:0044453
|
nuclear membrane part
|
3
|
5.6132016808583074E-5
|
| 16 | GO:0043170
|
macromolecule metabolic process
|
2
|
2.5143288578896916E-7
|
| 17 | GO:0006139
|
nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
|
3
|
3.143631149125584E-5
|
| 18 | GO:0018394
|
peptidyl-lysine acetylation
|
8
|
0.03153274700177271
|
| 19 | GO:0022402
|
cell cycle process
|
2
|
1.162328865114876E-5
|
| 20 | GO:0044424
|
intracellular part
|
2
|
1.162902613466757E-9
|
| 21 | GO:0043227
|
membrane-bound organelle
|
2
|
8.031253291615319E-4
|
| 22 | GO:0008283
|
cell proliferation
|
2
|
0.012750885118255626
|
| 23 | GO:0009987
|
cellular process
|
1
|
1.2984218528649044E-4
|
| 24 | GO:0016251
|
general RNA polymerase II transcription factor
activity
|
3
|
0.03689838174134714
|
| 25 | GO:0016070
|
RNA metabolic process
|
4
|
0.03632184944555493
|
| 26 | GO:0006366
|
transcription from RNA polymerase II promoter
|
6
|
0.0017937806705203914
|
| 27 | GO:0003676
|
nucleic acid binding
|
2
|
9.83662319147375E-6
|
| 28 | GO:0007259
|
JAK-STAT cascade
|
6
|
0.033075571153484924
|
| 29 | GO:0005665
|
DNA-directed RNA polymerase II, core complex
|
4
|
2.7679043342329585E-4
|
| 30 | GO:0051603
|
proteolysis involved in cellular protein
catabolic process
|
6
|
0.00958251492270177
|
| 31 | GO:0031323
|
regulation of cellular metabolic process
|
3
|
7.410529396535151E-4
|
| 32 | GO:0008152
GO:0044238 |
metabolic process
primary metabolic process |
1
2 |
1.207459836161433E-11
8.714656340485501E-4 |
| 33 | GO:0044422
|
organelle part
|
1
|
2.0935166074814944E-11
|
| 34 | GO:0008565
|
protein transporter activity
|
3
|
0.00534714869951522
|
| 35 | GO:0009893
|
positive regulation of metabolic process
|
3
|
0.011414194670861877
|
| 36 | GO:0048468
|
cell development
|
2
|
5.818590692617774E-4
|
| 37 | GO:0051726
|
regulation of cell cycle
|
3
|
0.002680114068543284
|
| 38 | GO:0016772
|
transferase activity, transferring
phosphorus-containing groups
|
3
|
0.015326907966132378
|
| 39 | GO:0043226
|
organelle
|
1
|
2.7071000702333046E-9
|
| 40 | GO:0030528
|
transcription regulator activity
|
1
|
3.2188359012311404E-7
|
| 41 | GO:0005515
|
protein binding
|
2
|
2.0944942535295306E-14
|
| 42 | GO:0065009
|
regulation of a molecular function
|
2
|
0.04195964145229042
|
| 43 | GO:0050794
|
regulation of cellular process
|
2
|
6.221882624442272E-7
|
| 44 | GO:0005643
|
nuclear pore
|
3
|
0.01791548294245392
|
| 45 | GO:0048522
|
positive regulation of cellular process
|
3
|
0.0016898283215360343
|
| 46 | GO:0043233
GO:0031974 |
organelle lumen
membrane-enclosed lumen |
2
1 |
4.4697223637546053E-7
1.131330686421232E-16 |
| 47 | GO:0046983
|
protein dimerization activity
|
3
|
0.00951610620872887
|
| 48 | GO:0051427
|
hormone receptor binding
|
4
|
0.03019988180700874
|
| 49 | GO:0065007
|
biological regulation
|
1
|
1.0298290336889241E-7
|
| 50 | GO:0046914
|
transition metal ion binding
|
4
|
0.04330635495538514
|
| 51 | GO:0032502
|
developmental process
|
1
|
0.010646131348291902
|
| 52 | GO:0033036
|
macromolecule localization
|
2
|
0.031161633761042803
|
| 53 | GO:0045935
|
positive regulation of nucleobase, nucleoside,
nucleotide and nucleic acid metabolic process
|
5
|
0.02338864230335657
|
| 54 | GO:0005488
|
binding
|
1
|
6.12163667987217E-7
|
| 55 | GO:0005654
|
nucleoplasm
|
4
|
0.004418739693382418
|
| 56 | GO:0043231
|
intracellular membrane-bound organelle
|
3
|
0.0023362107022586107
|
| 57 | GO:0044237
|
cellular metabolic process
|
2
|
9.54332938921256E-9
|
| 58 | GO:0051325
|
interphase
|
4
|
0.010024848439191445
|
| 59 | GO:0051318
|
G1 phase
|
4
|
0.0034932767488883767
|
| 60 | GO:0005952
|
cAMP-dependent protein kinase complex
|
3
|
0.028575547669826062
|
| 61 | GO:0017038
GO:0006606 |
protein import
protein import into nucleus |
4
5 |
0.0011858933177549828
0.049211783187228145 |
| 62 | GO:0019222
|
regulation of metabolic process
|
2
|
1.3917370322733498E-4
|
| 63 | GO:0016740
|
transferase activity
|
2
|
0.00179409165794916
|
| 64 | GO:0007498
|
mesoderm development
|
4
|
0.015131589800801985
|
| 65 | GO:0005634
|
nucleus
|
4
|
1.2584507717785205E-11
|
| 66 | GO:0008186
|
RNA-dependent ATPase activity
|
9
|
0.03575126864179498
|
| 67 | GO:0045941
|
positive regulation of transcription
|
6
|
0.027085038206261854
|
| 68 | GO:0016591
|
DNA-directed RNA polymerase II, holoenzyme
|
3
|
3.1134386190532264E-6
|
| 69 | GO:0032991
|
macromolecular complex
|
1
|
1.484173066206846E-16
|
| 70 | GO:0012505
|
endomembrane system
|
3
|
2.660009982923228E-4
|
| 71 | GO:0022607
GO:0065003 |
cellular component assembly
macromolecular complex assembly |
3
3 |
0.002367651119315697
0.004274525429570727 |
| 72 | GO:0001666
|
response to hypoxia
|
3
|
0.03669586961584067
|
| 73 | GO:0008022
|
protein C-terminus binding
|
3
|
0.0015556340877705143
|
| 74 | GO:0005667
|
transcription factor complex
|
3
|
0.011852747062372245
|
| 75 | GO:0005829
|
cytosol
|
4
|
4.033087491942231E-5
|
| 76 | GO:0004680
|
casein kinase activity
|
7
|
0.04008800251670959
|
| 77 | GO:0051649
GO:0046907 |
establishment of cellular localization
intracellular transport |
2
3 |
1.126628678081428E-5
4.354730949039702E-7 |
| 78 | GO:0048869
|
cellular developmental process
|
2
|
0.010391803668055352
|
| 79 | GO:0005048
|
signal sequence binding
|
3
|
0.002936734025683402
|
| 80 | GO:0016265
GO:0008219 |
death
cell death |
2
3 |
3.263899837246548E-4
0.0022633736303712656 |
| 81 | GO:0048518
|
positive regulation of biological process
|
3
|
1.2756442193153248E-4
|
| 82 | GO:0043623
|
cellular protein complex assembly
|
5
|
0.009458435022808544
|
| 83 | GO:0043283
|
biopolymer metabolic process
|
3
|
0.003463875773861413
|
| 84 | GO:0044428
|
nuclear part
|
3
|
1.163107221076485E-10
|
| 85 | GO:0008134
|
transcription factor binding
|
3
|
0.0033873706351605914
|
| 86 | GO:0051169
|
nuclear transport
|
4
|
2.3235531960134773E-5
|
| 87 | GO:0043067
|
regulation of programmed cell death
|
3
|
0.028554164587401804
|
| 88 | GO:0044451
|
nucleoplasm part
|
4
|
0.03265032225491107
|
| 89 | GO:0016055
|
Wnt receptor signaling pathway
|
5
|
0.042348863972306125
|
Mycoplasma
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0042611
|
MHC protein complex
|
3
|
0.03480888609152408
|
Neisseria
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0030099
|
myeloid cell differentiation
|
4
|
0.02639771430242688
|
| 2 | GO:0019538
GO:0044260 |
protein metabolic process
cellular macromolecule metabolic process |
3
3 |
0.014422984051951934
0.007606153506087565 |
| 3 | GO:0060089
|
molecular transducer activity
|
1
|
3.528976865446896E-8
|
| 4 | GO:0009611
GO:0009605 GO:0006950 GO:0006954 GO:0006952 |
response to wounding
response to external stimulus response to stress inflammatory response defense response |
3
2 2 3 2 |
9.051934946337916E-4
5.696476932146962E-4 0.033591864721646415 0.01289235159205411 1.774850563631604E-4 |
| 5 | GO:0008329
|
pattern recognition receptor activity
|
4
|
0.02382079414354309
|
| 6 | GO:0045087
|
innate immune response
|
3
|
0.02354714728897287
|
| 7 | GO:0001871
|
pattern binding
|
2
|
0.00589807188501648
|
| 8 | GO:0051606
|
detection of stimulus
|
2
|
0.03721528466107503
|
| 9 | GO:0005515
|
protein binding
|
2
|
0.025617791069968553
|
| 10 | GO:0007154
|
cell communication
|
2
|
0.010018600531663905
|
| 11 | GO:0009893
GO:0048522 GO:0031323 GO:0048518 GO:0031325 GO:0019222 |
positive regulation of metabolic process
positive regulation of cellular process regulation of cellular metabolic process positive regulation of biological process positive regulation of cellular metabolic process regulation of metabolic process |
3
3 3 3 4 2 |
1.1119545155290584E-5
4.035020411387696E-4 0.005815934295017174 5.242091072955651E-4 1.2087254901248298E-5 0.004705030604850826 |
| 12 | GO:0045357
|
regulation of interferon-beta biosynthetic
process
|
5
|
0.037475627158124004
|
| 13 | GO:0005121
|
Toll binding
|
4
|
0.030114655249037066
|
| 14 | GO:0050896
GO:0002376 GO:0006955 |
response to stimulus
immune system process immune response |
1
1 2 |
1.3281438967909445E-4
1.051551827902985E-7 1.318784585948813E-4 |
| 15 | GO:0043235
|
receptor complex
|
3
|
0.02550801947047808
|
| 16 | GO:0016020
|
membrane
|
2
|
0.0011234295390033897
|
| 17 | GO:0001530
|
lipopolysaccharide binding
|
3
|
0.025249256425655862
|
| 18 | GO:0009891
GO:0009058 GO:0009889 GO:0042107 GO:0006412 GO:0042089 GO:0009059 GO:0042035 GO:0031326 GO:0045727 GO:0044249 GO:0051247 GO:0051246 GO:0006417 GO:0001816 GO:0031328 |
positive regulation of biosynthetic process
biosynthetic process regulation of biosynthetic process cytokine metabolic process translation cytokine biosynthetic process macromolecule biosynthetic process regulation of cytokine biosynthetic process regulation of cellular biosynthetic process positive regulation of protein biosynthetic process cellular biosynthetic process positive regulation of protein metabolic process regulation of protein metabolic process regulation of translation cytokine production positive regulation of cellular biosynthetic process |
4
2 3 5 4 3 3 4 4 5 3 4 3 4 2 5 |
2.5871799768421513E-4
0.0012194369275986292 2.968621326420634E-6 1.1112936171985427E-7 0.0010359933899520897 1.4877996229400139E-5 1.2278443339880902E-4 0.015140821075944087 6.704071858752307E-6 0.0025253079974325854 6.283906866445213E-5 4.103238825531355E-4 9.918444474841517E-6 0.002689184609249192 1.091274913982777E-7 1.7502738012303894E-4 |
| 19 | GO:0007243
GO:0007249 |
protein kinase cascade
I-kappaB kinase/NF-kappaB cascade |
5
6 |
0.02581937654021101
0.023161180779130725 |
| 20 | GO:0009607
GO:0051704 |
response to biotic stimulus
multi-organism process |
2
1 |
0.034417096022858695
3.2333109175525275E-4 |
| 21 | GO:0003727
|
single-stranded RNA binding
|
4
|
0.025529991539916596
|
| 22 | GO:0035197
|
siRNA binding
|
4
|
3.929064206313298E-4
|
Papillomavirus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0009719
|
response to endogenous stimulus
|
2
|
0.03955410090753938
|
| 2 | GO:0031974
GO:0043233 |
membrane-enclosed lumen
organelle lumen |
1
2 |
2.1130413598266247E-10
2.4937679772922105E-4 |
| 3 | GO:0050794
|
regulation of cellular process
|
2
|
4.88464451574983E-9
|
| 4 | GO:0043229
GO:0043226 |
intracellular organelle
organelle |
2
1 |
0.01281070403380014
1.0603579949458433E-7 |
| 5 | GO:0046930
|
pore complex
|
5
|
2.205788092913902E-6
|
| 6 | GO:0019219
|
regulation of nucleobase, nucleoside, nucleotide
and nucleic acid metabolic process
|
4
|
0.0043531334800456034
|
| 7 | GO:0051726
|
regulation of cell cycle
|
3
|
3.728491150822862E-7
|
| 8 | GO:0003676
|
nucleic acid binding
|
2
|
0.011571565365243196
|
| 9 | GO:0045786
|
negative regulation of progression through cell
cycle
|
4
|
0.03504332305785452
|
| 10 | GO:0065007
|
biological regulation
|
1
|
1.1643034426269662E-9
|
| 11 | GO:0051318
|
G1 phase
|
4
|
0.01161120262523712
|
| 12 | GO:0032991
|
macromolecular complex
|
1
|
2.1620286732089426E-5
|
| 13 | GO:0005515
|
protein binding
|
2
|
4.212254859449362E-6
|
| 14 | GO:0046907
|
intracellular transport
|
3
|
0.02233172143032216
|
| 15 | GO:0022402
|
cell cycle process
|
2
|
3.9690990052647023E-13
|
| 16 | GO:0018394
|
peptidyl-lysine acetylation
|
8
|
0.011070820453859995
|
| 17 | GO:0005829
|
cytosol
|
4
|
0.0014083795125760317
|
| 18 | GO:0005035
|
death receptor activity
|
5
|
0.015758318901791368
|
| 19 | GO:0044453
|
nuclear membrane part
|
3
|
0.007044746838975525
|
| 20 | GO:0009987
|
cellular process
|
1
|
0.0034556446216874133
|
| 21 | GO:0016265
GO:0008219 |
death
cell death |
2
3 |
0.0016162651305866504
0.004291827760885079 |
| 22 | GO:0005694
|
chromosome
|
4
|
0.006239109293126636
|
| 23 | GO:0044451
|
nucleoplasm part
|
4
|
0.003974669238603919
|
| 24 | GO:0016043
|
cellular component organization and biogenesis
|
2
|
0.004675861582495531
|
| 25 | GO:0031323
GO:0019222 |
regulation of cellular metabolic process
regulation of metabolic process |
3
2 |
3.5926589485358988E-6
3.6314576186840923E-6 |
| 26 | GO:0006259
|
DNA metabolic process
|
4
|
7.72812281138447E-6
|
| 27 | GO:0003677
|
DNA binding
|
3
|
0.0012520782351783549
|
| 28 | GO:0005654
|
nucleoplasm
|
4
|
0.010811528752083552
|
| 29 | GO:0005667
|
transcription factor complex
|
3
|
1.0319171006750168E-5
|
| 30 | GO:0018193
|
peptidyl-amino acid modification
|
6
|
0.02278738575521607
|
| 31 | GO:0030528
|
transcription regulator activity
|
1
|
3.869729060516783E-10
|
| 32 | GO:0005488
|
binding
|
1
|
1.6435005754683978E-4
|
| 33 | GO:0044422
GO:0044446 |
organelle part
intracellular organelle part |
1
2 |
9.72451955351116E-8
1.9165896015604187E-4 |
| 34 | GO:0006350
|
transcription
|
4
|
0.0390772088220938
|
| 35 | GO:0016570
|
histone modification
|
7
|
0.044928859629949955
|
| 36 | GO:0051427
|
hormone receptor binding
|
4
|
0.02685031398610862
|
| 37 | GO:0044428
|
nuclear part
|
3
|
4.9975879845166425E-6
|
| 38 | GO:0065009
|
regulation of a molecular function
|
2
|
0.003785904964249066
|
| 39 | GO:0008152
|
metabolic process
|
1
|
2.188604685272327E-6
|
| 40 | GO:0030111
|
regulation of Wnt receptor signaling pathway
|
4
|
0.04520323933295671
|
| 41 | GO:0005622
|
intracellular
|
2
|
9.252860828937557E-4
|
| 42 | GO:0042325
GO:0019220 |
regulation of phosphorylation
regulation of phosphate metabolic process |
6
5 |
0.04482479717868149
0.03466096144980973 |
| 43 | GO:0007049
|
cell cycle
|
2
|
2.8502964604477765E-14
|
| 44 | GO:0048522
|
positive regulation of cellular process
|
3
|
0.03700165017217864
|
| 45 | GO:0005048
GO:0008565 |
signal sequence binding
protein transporter activity |
3
3 |
0.005091533053740458
0.02335902441759471 |
| 46 | GO:0016070
|
RNA metabolic process
|
4
|
0.015917777903294347
|
| 47 | GO:0006139
|
nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
|
3
|
1.0218572028839836E-4
|
| 48 | GO:0065003
|
macromolecular complex assembly
|
3
|
0.023876119848381453
|
| 49 | GO:0005634
|
nucleus
|
4
|
4.083167654727371E-6
|
| 50 | GO:0044237
|
cellular metabolic process
|
2
|
8.070128612096645E-5
|
| 51 | GO:0008134
|
transcription factor binding
|
3
|
2.211305532531806E-4
|
| 52 | GO:0044424
|
intracellular part
|
2
|
7.784134684374265E-5
|
| 53 | GO:0043170
|
macromolecule metabolic process
|
2
|
2.1662476643206948E-4
|
Plasmodium
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0007272
|
ensheathment of neurons
|
2
|
0.0382085570040776
|
Pseudomonas
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0051179
GO:0051234 |
localization
establishment of localization |
1
1 |
0.02834911492431386
0.011841979088077282 |
| 2 | GO:0031644
|
regulation of neurological process
|
3
|
0.005059803837062347
|
| 3 | GO:0007154
|
cell communication
|
2
|
0.03844569354359971
|
| 4 | GO:0019904
|
protein domain specific binding
|
3
|
2.710637939638437E-9
|
| 5 | GO:0008426
|
protein kinase C inhibitor activity
|
5
|
0.013065953018878794
|
| 6 | GO:0016358
|
dendrite development
|
3
|
0.02761096164184652
|
| 7 | GO:0048869
GO:0048468 |
cellular developmental process
cell development |
2
2 |
0.038738013035068485
0.016164449415413826 |
| 8 | GO:0016043
|
cellular component organization and biogenesis
|
2
|
0.014079942684881585
|
| 9 | GO:0005159
|
insulin-like growth factor receptor binding
|
4
|
0.03577366703256937
|
Salmonella
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0043552
GO:0042995 GO:0051128 GO:0030742 GO:0043550 |
positive regulation of phosphoinositide 3-kinase
activity
cell projection regulation of cellular component organization and biogenesis GTP-dependent protein binding regulation of lipid kinase activity |
6
2 3 3 6 |
0.015552130762248139
0.030715213544126835 0.015934127311103476 4.1595029795143604E-4 0.031414906778678184 |
Sarcoma virus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0006139
|
nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
|
3
|
0.040103274732032776
|
| 2 | GO:0016265
GO:0008219 |
death
cell death |
2
3 |
0.005746809708228739
0.03933541769578626 |
| 3 | GO:0031967
GO:0031975 |
organelle envelope
envelope |
2
1 |
0.04060787785198419
0.008482912180732967 |
| 4 | GO:0003682
|
chromatin binding
|
2
|
0.04880631713924912
|
| 5 | GO:0048869
GO:0048468 |
cellular developmental process
cell development |
2
2 |
0.0403436104695157
0.005457345080321329 |
| 6 | GO:0030894
|
replisome
|
3
|
0.009424564370877997
|
| 7 | GO:0000151
|
ubiquitin ligase complex
|
3
|
0.0417107755974198
|
| 8 | GO:0045792
GO:0045926 GO:0016049 GO:0043086 GO:0030308 |
negative regulation of cell size
negative regulation of growth cell growth negative regulation of enzyme activity negative regulation of cell growth |
4
3 2 4 4 |
0.03903890933064412
0.020921159726712196 0.039612535813526084 0.046163665703725376 0.009994908454863852 |
| 9 | GO:0051169
|
nuclear transport
|
4
|
0.039942495046040916
|
| 10 | GO:0031323
GO:0019222 |
regulation of cellular metabolic process
regulation of metabolic process |
3
2 |
0.03868302816314247
0.03753744555518407 |
| 11 | GO:0046425
GO:0045763 GO:0000159 GO:0046426 GO:0050732 |
regulation of JAK-STAT cascade
negative regulation of amino acid metabolic process protein phosphatase type 2A complex negative regulation of JAK-STAT cascade negative regulation of peptidyl-tyrosine phosphorylation |
4
5 3 5 5 |
0.04124033255945666
0.041736014373376595 0.04861043487305383 0.04027912459789136 0.03401389274432307 |
| 12 | GO:0005488
|
binding
|
1
|
0.04039130751110917
|
| 13 | GO:0030155
|
regulation of cell adhesion
|
3
|
0.04296471065665624
|
| 14 | GO:0044424
GO:0005622 |
intracellular part
intracellular |
2
2 |
0.010024331761177225
0.03709717038241188 |
| 15 | GO:0012505
|
endomembrane system
|
3
|
0.047625907262327224
|
| 16 | GO:0008152
GO:0043170 |
metabolic process
macromolecule metabolic process |
1
2 |
0.0016434220982650609
0.03794184861813601 |
| 17 | GO:0022402
GO:0007049 |
cell cycle process
cell cycle |
2
2 |
0.004521665469218731
0.008951672205873059 |
| 18 | GO:0043566
|
structure-specific DNA binding
|
4
|
0.004614309303989043
|
| 19 | GO:0016055
|
Wnt receptor signaling pathway
|
5
|
0.032606536988011636
|
| 20 | GO:0005662
|
DNA replication factor A complex
|
3
|
0.03764503837972477
|
| 21 | GO:0046907
GO:0051649 |
intracellular transport
establishment of cellular localization |
3
2 |
0.03681488051785756
0.04917574082499345 |
| 22 | GO:0044237
|
cellular metabolic process
|
2
|
0.005206045569119512
|
| 23 | GO:0051726
|
regulation of cell cycle
|
3
|
0.037491934719440075
|
| 24 | GO:0043226
|
organelle
|
1
|
0.02414520240426897
|
| 25 | GO:0005070
|
SH3/SH2 adaptor activity
|
3
|
0.04350955397189733
|
| 26 | GO:0016043
|
cellular component organization and biogenesis
|
2
|
0.039653433130659076
|
| 27 | GO:0005515
|
protein binding
|
2
|
0.0019445215986989405
|
| 28 | GO:0006974
|
response to DNA damage stimulus
|
3
|
0.03375911800262604
|
| 29 | GO:0030528
|
transcription regulator activity
|
1
|
0.0327402084197228
|
| 30 | GO:0043204
|
perikaryon
|
2
|
0.04893341553597933
|
| 31 | GO:0046930
|
pore complex
|
5
|
0.007597957205535821
|
| 32 | GO:0032991
|
macromolecular complex
|
1
|
0.033009651450858345
|
| 33 | GO:0003677
|
DNA binding
|
3
|
0.04454415462288398
|
| 34 | GO:0044428
|
nuclear part
|
3
|
0.005780447615418034
|
| 35 | GO:0031974
|
membrane-enclosed lumen
|
1
|
0.0021381842724294917
|
| 36 | GO:0051427
|
hormone receptor binding
|
4
|
0.03984564496975996
|
| 37 | GO:0006259
|
DNA metabolic process
|
4
|
0.0042371285377288655
|
| 38 | GO:0005634
|
nucleus
|
4
|
0.027414886966941453
|
| 39 | GO:0044422
GO:0044446 |
organelle part
intracellular organelle part |
1
2 |
0.0018789275477205968
0.03670084543858444 |
| 40 | GO:0008639
|
small protein conjugating enzyme activity
|
2
|
0.03992590957334974
|
| 41 | GO:0016363
|
nuclear matrix
|
4
|
0.04700369006640455
|
| 42 | GO:0006607
|
NLS-bearing substrate import into nucleus
|
6
|
0.047684911569325764
|
Staphylococcus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0050896
|
response to stimulus
|
1
|
7.050261854105687E-5
|
Stomatitis virus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0005643
GO:0031975 GO:0051236 GO:0044453 GO:0015931 |
nuclear pore
envelope establishment of RNA localization nuclear membrane part nucleobase, nucleoside, nucleotide and nucleic acid transport |
3
1 2 3 3 |
0.03622793395301687
0.04196304040654997 0.0426819484477116 0.049122334787831935 0.034326712737523274 |
Streptococcus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0002376
|
immune system process
|
1
|
0.013597797647541647
|
| 2 | GO:0042611
|
MHC protein complex
|
3
|
0.03444247676424488
|
| 3 | GO:0050896
|
response to stimulus
|
1
|
0.044574485387882154
|
| 4 | GO:0008147
|
structural constituent of bone
|
2
|
0.008699478823189387
|
| 5 | GO:0044421
|
extracellular region part
|
1
|
0.03951610167153628
|
T-lymphotrophic virus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0050794
GO:0065007 |
regulation of cellular process
biological regulation |
2
1 |
0.0019726972362591956
0.001908346652127699 |
Tula virus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0032879
|
regulation of localization
|
2
|
0.018277912280140807
|
Virus
| Group | Function(s) | Description(s) | Depth | p-value(s) (FDR Corrected) |
|---|---|---|---|---|
| 1 | GO:0008094
|
DNA-dependent ATPase activity
|
9
|
0.01524043402321963
|
| 2 | GO:0005622
|
intracellular
|
2
|
1.7244815829947798E-7
|
| 3 | GO:0043687
|
post-translational protein modification
|
6
|
0.03873877846487015
|
| 4 | GO:0006366
|
transcription from RNA polymerase II promoter
|
6
|
7.982703153391538E-5
|
| 5 | GO:0006520
|
amino acid metabolic process
|
4
|
0.03184789576645916
|
| 6 | GO:0008537
GO:0008538 |
proteasome activator complex
proteasome activator activity |
3
3 |
0.046812556523323494
0.01259036862064717 |
| 7 | GO:0048522
|
positive regulation of cellular process
|
3
|
2.2124429305190367E-6
|
| 8 | GO:0065009
|
regulation of a molecular function
|
2
|
0.03686774260785279
|
| 9 | GO:0051726
|
regulation of cell cycle
|
3
|
0.005015794130470528
|
| 10 | GO:0016410
|
N-acyltransferase activity
|
6
|
0.004885521756420106
|
| 11 | GO:0006139
|
nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
|
3
|
8.833267171547357E-13
|
| 12 | GO:0005634
|
nucleus
|
4
|
7.0362085082616636E-34
|
| 13 | GO:0003676
|
nucleic acid binding
|
2
|
1.4021692139337882E-11
|
| 14 | GO:0005942
|
phosphoinositide 3-kinase complex
|
3
|
0.047144771958199896
|
| 15 | GO:0055082
|
cellular chemical homeostasis
|
3
|
0.015375324645158313
|
| 16 | GO:0008283
|
cell proliferation
|
2
|
0.003522168380095762
|
| 17 | GO:0002376
|
immune system process
|
1
|
1.4979084280951313E-12
|
| 18 | GO:0019725
|
cellular homeostasis
|
2
|
0.009437206467298571
|
| 19 | GO:0006334
GO:0031497 |
nucleosome assembly
chromatin assembly |
5
4 |
0.0016138873871900598
1.9936311208099148E-7 |
| 20 | GO:0002521
|
leukocyte differentiation
|
4
|
0.0025134087901914144
|
| 21 | GO:0008380
|
RNA splicing
|
6
|
0.013841800759934849
|
| 22 | GO:0002520
GO:0048534 |
immune system development
hemopoietic or lymphoid organ development |
2
3 |
0.014594194637487254
1.2555049212273415E-4 |
| 23 | GO:0006928
GO:0051674 |
cell motility
localization of cell |
2
2 |
0.010012089556349885
0.0011213458985509387 |
| 24 | GO:0018108
|
peptidyl-tyrosine phosphorylation
|
7
|
0.009539116101354224
|
| 25 | GO:0042110
|
T cell activation
|
4
|
0.03471877626968003
|
| 26 | GO:0032393
|
MHC class I receptor activity
|
5
|
0.015127584124586124
|
| 27 | GO:0044428
|
nuclear part
|
3
|
2.270995576566754E-21
|
| 28 | GO:0043283
|
biopolymer metabolic process
|
3
|
5.1441630121061E-7
|
| 29 | GO:0051276
|
chromosome organization and biogenesis
|
4
|
1.0802737193926647E-4
|
| 30 | GO:0008243
|
plasminogen activator activity
|
6
|
0.04655929407501597
|
| 31 | GO:0001948
|
glycoprotein binding
|
3
|
0.02935935204607408
|
| 32 | GO:0001772
|
immunological synapse
|
4
|
0.002816554834297329
|
| 33 | GO:0015026
|
coreceptor activity
|
4
|
0.024185296429539413
|
| 34 | GO:0005487
|
nucleocytoplasmic transporter activity
|
2
|
2.2793454258345926E-4
|
| 35 | GO:0016251
|
general RNA polymerase II transcription factor
activity
|
3
|
0.010517997268295599
|
| 36 | GO:0008601
|
protein phosphatase type 2A regulator activity
|
4
|
0.011353912046346122
|
| 37 | GO:0048468
|
cell development
|
2
|
2.186576670460231E-8
|
| 38 | GO:0016849
GO:0009190 |
phosphorus-oxygen lyase activity
cyclic nucleotide biosynthetic process |
3
5 |
8.030263287331927E-5
0.03712888776229661 |
| 39 | GO:0019208
|
phosphatase regulator activity
|
2
|
0.008025609213311198
|
| 40 | GO:0030163
|
protein catabolic process
|
4
|
0.0012696358938441331
|
| 41 | GO:0042330
|
taxis
|
3
|
0.010356542938367313
|
| 42 | GO:0044446
|
intracellular organelle part
|
2
|
1.7669296865145674E-10
|
| 43 | GO:0042101
|
T cell receptor complex
|
4
|
0.0063456940778246285
|
| 44 | GO:0007049
|
cell cycle
|
2
|
2.3860193790465065E-5
|
| 45 | GO:0000159
|
protein phosphatase type 2A complex
|
3
|
2.3267506777619128E-7
|
| 46 | GO:0016265
GO:0008219 |
death
cell death |
2
3 |
2.11507388343674E-15
1.0357857456241098E-9 |
| 47 | GO:0006955
|
immune response
|
2
|
0.0019816780915878135
|
| 48 | GO:0004114
|
3',5'-cyclic-nucleotide phosphodiesterase
activity
|
7
|
0.0
|
| 49 | GO:0044451
|
nucleoplasm part
|
4
|
0.01860662777402989
|
| 50 | GO:0044424
|
intracellular part
|
2
|
7.210836798814093E-13
|
| 51 | GO:0003713
|
transcription coactivator activity
|
3
|
0.04306524277277776
|
| 52 | GO:0005838
|
proteasome regulatory particle (sensu Eukaryota)
|
3
|
3.80381231394263E-6
|
| 53 | GO:0006383
|
transcription from RNA polymerase III promoter
|
6
|
2.5791739416417523E-4
|
| 54 | GO:0030530
|
heterogeneous nuclear ribonucleoprotein complex
|
3
|
5.92355043701134E-5
|
| 55 | GO:0008152
|
metabolic process
|
1
|
1.237926643638411E-9
|
| 56 | GO:0043233
GO:0031974 |
organelle lumen
membrane-enclosed lumen |
2
1 |
4.7920321376953534E-5
3.642043344395804E-16 |
| 57 | GO:0009893
|
positive regulation of metabolic process
|
3
|
0.021523820907118744
|
| 58 | GO:0019222
|
regulation of metabolic process
|
2
|
1.3257563276729208E-4
|
| 59 | GO:0003899
|
DNA-directed RNA polymerase activity
|
5
|
5.670077649842263E-4
|
| 60 | GO:0022415
|
viral reproductive process
|
2
|
2.0198522550342916E-15
|
| 61 | GO:0016684
GO:0004602 |
oxidoreductase activity, acting on peroxide as
acceptor
glutathione peroxidase activity |
3
3 |
0.02787095853305602
0.0 |
| 62 | GO:0046870
|
cadmium ion binding
|
5
|
0.0
|
| 63 | GO:0042613
|
MHC class II protein complex
|
4
|
0.047583260233971206
|
| 64 | GO:0006521
GO:0033238 GO:0001932 |
regulation of amino acid metabolic process
regulation of amine metabolic process regulation of protein amino acid phosphorylation |
5
4 6 |
9.083360121716961E-5
0.005504952159661432 0.009778949445501613 |
| 65 | GO:0050792
|
regulation of viral life cycle
|
2
|
1.593313972015023E-5
|
| 66 | GO:0009607
|
response to biotic stimulus
|
2
|
0.005895306362167314
|
| 67 | GO:0044238
|
primary metabolic process
|
2
|
1.7928764562354186E-10
|
| 68 | GO:0043227
|
membrane-bound organelle
|
2
|
3.5097973919000405E-6
|
| 69 | GO:0048525
|
negative regulation of viral life cycle
|
3
|
0.014588856753497224
|
| 70 | GO:0000805
GO:0001740 GO:0007549 |
X chromosome
Barr body dosage compensation |
6
7 4 |
0.0
0.0 0.0 |
| 71 | GO:0012505
|
endomembrane system
|
3
|
4.409534894229915E-9
|
| 72 | GO:0044427
|
chromosomal part
|
3
|
1.6653965175520564E-7
|
| 73 | GO:0022607
|
cellular component assembly
|
3
|
3.77337221202358E-12
|
| 74 | GO:0044421
|
extracellular region part
|
1
|
0.0030467069078917186
|
| 75 | GO:0050896
|
response to stimulus
|
1
|
1.9051978508713535E-15
|
| 76 | GO:0042578
|
phosphoric ester hydrolase activity
|
4
|
1.0295953084141113E-4
|
| 77 | GO:0015085
|
calcium ion transmembrane transporter activity
|
6
|
0.010211129140250906
|
| 78 | GO:0051649
|
establishment of cellular localization
|
2
|
8.185289722043398E-8
|
| 79 | GO:0003712
|
transcription cofactor activity
|
2
|
0.0034271423063667304
|
| 80 | GO:0006468
|
protein amino acid phosphorylation
|
6
|
0.013146935690334108
|
| 81 | GO:0043256
|
laminin complex
|
2
|
0.011802782669779837
|
| 82 | GO:0016779
|
nucleotidyltransferase activity
|
4
|
7.108819956678859E-4
|
| 83 | GO:0050730
|
regulation of peptidyl-tyrosine phosphorylation
|
4
|
0.001239407964011167
|
| 84 | GO:0065003
|
macromolecular complex assembly
|
3
|
1.1043075984844299E-13
|
| 85 | GO:0031323
|
regulation of cellular metabolic process
|
3
|
6.814136700256224E-4
|
| 86 | GO:0042325
|
regulation of phosphorylation
|
6
|
0.0067907413246153445
|
| 87 | GO:0001816
|
cytokine production
|
2
|
0.012293261652063094
|
| 88 | GO:0051603
GO:0044257 |
proteolysis involved in cellular protein
catabolic process
cellular protein catabolic process |
6
5 |
0.0014231968678782515
0.02359244921685132 |
| 89 | GO:0000785
|
chromatin
|
4
|
3.852906231456759E-6
|
| 90 | GO:0004722
|
protein serine/threonine phosphatase activity
|
7
|
0.015078268885251997
|
| 91 | GO:0031965
|
nuclear membrane
|
3
|
4.308418439269217E-9
|
| 92 | GO:0005666
|
DNA-directed RNA polymerase III complex
|
5
|
0.02748111473506312
|
| 93 | GO:0030528
|
transcription regulator activity
|
1
|
5.6929710882740625E-12
|
| 94 | GO:0046902
|
regulation of mitochondrial membrane permeability
|
5
|
0.005522885117867513
|
| 95 | GO:0016071
|
mRNA metabolic process
|
5
|
0.010080240721921761
|
| 96 | GO:0032395
|
MHC class II receptor activity
|
5
|
0.01843895961772427
|
| 97 | GO:0016591
|
DNA-directed RNA polymerase II, holoenzyme
|
3
|
6.317754269471853E-6
|
| 98 | GO:0005829
|
cytosol
|
4
|
3.120682807360374E-22
|
| 99 | GO:0009187
|
cyclic nucleotide metabolic process
|
5
|
1.1272632020419633E-4
|
| 100 | GO:0004428
|
inositol or phosphatidylinositol kinase activity
|
5
|
0.020285460203490473
|
| 101 | GO:0032991
|
macromolecular complex
|
1
|
2.6348805542200838E-48
|
| 102 | GO:0006333
|
chromatin assembly or disassembly
|
7
|
1.0008524511309461E-7
|
| 103 | GO:0015101
|
organic cation transmembrane transporter activity
|
6
|
0.02763174721562916
|
| 104 | GO:0004016
GO:0009975 |
adenylate cyclase activity
cyclase activity |
3
2 |
0.009356264357338781
0.018236177260573215 |
| 105 | GO:0004697
GO:0001565 |
protein kinase C activity
phorbol ester receptor activity |
5
4 |
3.5187857044855604E-5
3.809569348349383E-6 |
| 106 | GO:0005952
|
cAMP-dependent protein kinase complex
|
3
|
0.0016463622162782253
|
| 107 | GO:0006354
|
RNA elongation
|
5
|
1.399126767888352E-4
|
| 108 | GO:0005488
|
binding
|
1
|
3.420289629735893E-10
|
| 109 | GO:0050865
|
regulation of cell activation
|
3
|
0.02418603407835278
|
| 110 | GO:0005635
|
nuclear envelope
|
3
|
2.6386858942036674E-7
|
| 111 | GO:0005515
|
protein binding
|
2
|
2.0951709743293893E-15
|
| 112 | GO:0008603
|
cAMP-dependent protein kinase regulator activity
|
4
|
0.04776218637631253
|
| 113 | GO:0043285
|
biopolymer catabolic process
|
4
|
0.047616342197545174
|
| 114 | GO:0043067
|
regulation of programmed cell death
|
3
|
9.932013719132466E-8
|
| 115 | GO:0003677
|
DNA binding
|
3
|
0.031863693123151855
|
| 116 | GO:0001727
GO:0035004 |
lipid kinase activity
phosphoinositide 3-kinase activity |
5
6 |
0.013635627389955059
0.002093363939494203 |
| 117 | GO:0031594
|
neuromuscular junction
|
2
|
0.024470425099360694
|
| 118 | GO:0000502
|
proteasome complex (sensu Eukaryota)
|
3
|
2.342461216728023E-22
|
| 119 | GO:0065004
|
protein-DNA complex assembly
|
4
|
1.965191647162829E-9
|
| 120 | GO:0008287
|
protein serine/threonine phosphatase complex
|
2
|
5.081936893143944E-7
|
| 121 | GO:0005643
|
nuclear pore
|
3
|
2.9042345534575113E-8
|
| 122 | GO:0008134
|
transcription factor binding
|
3
|
1.7430425788525092E-7
|
| 123 | GO:0004298
|
threonine endopeptidase activity
|
5
|
8.237096457725022E-11
|
| 124 | GO:0043170
|
macromolecule metabolic process
|
2
|
3.2870143337519318E-12
|
| 125 | GO:0065007
|
biological regulation
|
1
|
3.4551244580577857E-12
|
| 126 | GO:0001775
|
cell activation
|
2
|
3.256941834489332E-5
|
| 127 | GO:0045995
|
regulation of embryonic development
|
3
|
0.04679738416222123
|
| 128 | GO:0005663
|
DNA replication factor C complex
|
3
|
0.04761434171432153
|
| 129 | GO:0051098
|
regulation of binding
|
3
|
0.030083383961794805
|
| 130 | GO:0006352
|
transcription initiation
|
5
|
0.001214123600134089
|
| 131 | GO:0001666
|
response to hypoxia
|
3
|
0.04772812650582913
|
| 132 | GO:0008430
|
selenium binding
|
2
|
0.02511526202772782
|
| 133 | GO:0046930
|
pore complex
|
5
|
9.040993135320112E-22
|
| 134 | GO:0005839
|
proteasome core complex (sensu Eukaryota)
|
3
|
4.317867704864064E-11
|
| 135 | GO:0005507
|
copper ion binding
|
5
|
6.857172740273852E-4
|
| 136 | GO:0046983
|
protein dimerization activity
|
3
|
0.01972378945291659
|
| 137 | GO:0017038
|
protein import
|
4
|
1.6810604775081297E-4
|
| 138 | GO:0048518
|
positive regulation of biological process
|
3
|
1.8014431961612696E-5
|
| 139 | GO:0004115
|
3',5'-cyclic-AMP phosphodiesterase activity
|
8
|
0.0
|
| 140 | GO:0009986
|
cell surface
|
2
|
0.03192852151382149
|
| 141 | GO:0030880
|
RNA polymerase complex
|
3
|
1.0447522317690942E-7
|
| 142 | GO:0035005
|
phosphatidylinositol-4-phosphate 3-kinase
activity
|
7
|
0.0
|
| 143 | GO:0018193
|
peptidyl-amino acid modification
|
6
|
0.021618928171978982
|
| 144 | GO:0044453
|
nuclear membrane part
|
3
|
1.860959361467054E-17
|
| 145 | GO:0006259
|
DNA metabolic process
|
4
|
1.6672114675909735E-5
|
| 146 | GO:0043226
|
organelle
|
1
|
0.002000834313008801
|
| 147 | GO:0030217
|
T cell differentiation
|
5
|
0.039627936640520105
|
| 148 | GO:0015630
|
microtubule cytoskeleton
|
5
|
0.033165139407327
|
| 149 | GO:0004175
|
endopeptidase activity
|
4
|
0.013228073840207735
|
| 150 | GO:0044422
|
organelle part
|
1
|
3.393271319463629E-17
|
| 151 | GO:0004693
|
cyclin-dependent protein kinase activity
|
7
|
0.011224770232980505
|
| 152 | GO:0008081
|
phosphoric diester hydrolase activity
|
5
|
2.3184005529382086E-7
|
| 153 | GO:0040011
|
locomotion
|
1
|
0.008093717577335466
|
| 154 | GO:0004112
|
cyclic-nucleotide phosphodiesterase activity
|
6
|
0.0
|
| 155 | GO:0008632
|
apoptotic program
|
5
|
0.015890666304372806
|
| 156 | GO:0051704
|
multi-organism process
|
1
|
9.818244887270768E-8
|
| 157 | GO:0051174
GO:0019220 |
regulation of phosphorus metabolic process
regulation of phosphate metabolic process |
4
5 |
0.011341936408939601
0.0025018965515637053 |
| 158 | GO:0006397
|
mRNA processing
|
6
|
0.004275189448829679
|
| 159 | GO:0009987
|
cellular process
|
1
|
3.5529114181392336E-6
|
| 160 | GO:0007172
|
signal complex assembly
|
6
|
0.01243445938792946
|
| 161 | GO:0009897
|
external side of plasma membrane
|
3
|
0.005226776772084395
|
| 162 | GO:0016043
|
cellular component organization and biogenesis
|
2
|
3.3045263389913E-7
|
| 163 | GO:0005667
|
transcription factor complex
|
3
|
6.016326844493613E-4
|
| 164 | GO:0044237
|
cellular metabolic process
|
2
|
2.333484024637267E-9
|
| 165 | GO:0015931
GO:0051236 GO:0006403 |
nucleobase, nucleoside, nucleotide and nucleic
acid transport
establishment of RNA localization RNA localization |
3
2 3 |
6.990976527997342E-13
4.516587750559356E-14 4.818772070321976E-12 |
| 166 | GO:0008139
|
nuclear localization sequence binding
|
4
|
0.006054531990438758
|
| 167 | GO:0047485
|
protein N-terminus binding
|
3
|
0.03906565052194857
|
| 168 | GO:0005694
|
chromosome
|
4
|
1.668399457524135E-15
|
| 169 | GO:0005021
|
vascular endothelial growth factor receptor
activity
|
7
|
0.04760769151221226
|
| 170 | GO:0001637
|
G-protein chemoattractant receptor activity
|
5
|
1.6711803052767672E-4
|
| 171 | GO:0001730
|
2'-5'-oligoadenylate synthetase activity
|
5
|
0.0
|
| 172 | GO:0043069
|
negative regulation of programmed cell death
|
4
|
0.003528503606966481
|
| 173 | GO:0048869
|
cellular developmental process
|
2
|
5.854631344181E-5
|
| 174 | GO:0016032
|
viral reproduction
|
1
|
5.654424376515603E-15
|
| 175 | GO:0050794
|
regulation of cellular process
|
2
|
3.7948249144135637E-10
|
| 176 | GO:0005654
|
nucleoplasm
|
4
|
0.012222908151342145
|
| 177 | GO:0043231
|
intracellular membrane-bound organelle
|
3
|
5.439718073310402E-6
|
| 178 | GO:0006325
|
establishment and/or maintenance of chromatin
architecture
|
6
|
0.04010384401367099
|
| 179 | GO:0022402
|
cell cycle process
|
2
|
1.0752364906138144E-4
|
| 180 | GO:0000786
|
nucleosome
|
3
|
1.2845879368008376E-22
|
| 181 | GO:0031325
|
positive regulation of cellular metabolic process
|
4
|
0.027744794321626513
|
| 182 | GO:0042089
|
cytokine biosynthetic process
|
3
|
0.002084342988898764
|
| 183 | GO:0046907
|
intracellular transport
|
3
|
3.117842737121516E-10
|
| 184 | GO:0022834
|
ligand-gated channel activity
|
6
|
0.047189285990638846
|
| 185 | GO:0004003
|
ATP-dependent DNA helicase activity
|
4
|
0.04243204545476102
|
| 186 | GO:0016563
|
transcription activator activity
|
2
|
0.004586664767084241
|
| 187 | GO:0003711
|
transcription elongation regulator activity
|
2
|
0.006705624724236749
|
| 188 | GO:0004652
|
polynucleotide adenylyltransferase activity
|
5
|
0.0
|
| 189 | GO:0031967
GO:0031975 |
organelle envelope
envelope |
2
1 |
0.003048784071193162
5.7904579009387765E-5 |
| 190 | GO:0016772
|
transferase activity, transferring
phosphorus-containing groups
|
3
|
8.09234318059434E-7
|
| 191 | GO:0030522
|
intracellular receptor-mediated signaling pathway
|
5
|
0.024296044635863885
|
| 192 | GO:0032943
|
mononuclear cell proliferation
|
3
|
0.008203522851551986
|
| 193 | GO:0006605
|
protein targeting
|
5
|
1.64081502307556E-6
|
| 194 | GO:0008022
|
protein C-terminus binding
|
3
|
0.008840258878035807
|
| 195 | GO:0051169
|
nuclear transport
|
4
|
2.567931562337426E-7
|